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Introduction to Vfend 50mg Tablet
The Vfend 50mg tablet is an antifungal medication containing the active ingredient Voriconazole. It falls under the category of fungal ergosterol synthesis inhibitors. This drug is prescribed for severe, life-threatening fungal infections and is also used as a preventive measure for high-risk individuals, such as those who have undergone bone marrow transplantation. It is important to note that this medication is not suitable for children under the age of 2.
Refrain from taking the Vfend 50mg tablet if you are allergic to Voriconazole or its components. Prior to using this medication, inform your doctor if you have experienced allergic reactions to other azoles, have a history of liver disease, or suffer from conditions such as cardiomyopathy, irregular heartbeat, slow heart rate, or ‘long QTc syndrome’ on an electrocardiogram (ECG). Additionally, it is imperative to avoid exposure to sunlight and UV rays during the course of treatment, ensuring skin protection with clothing and high-SPF sunscreen. Children should adhere to these precautions as well. Common side effects may include fever, rash, nausea, vomiting, diarrhea, headache, swelling of the extremities, stomach pain, and breathing difficulties.
While using the Vfend 50mg tablet, promptly notify your doctor if you encounter symptoms such as sunburn, severe skin rash or blisters, bone pain, signs of adrenal insufficiency (persistent fatigue, muscle weakness, loss of appetite, weight loss, abdominal pain), or indications of Cushing’s syndrome (weight gain, fatty hump, rounded face, darkened skin, thinning skin, easy bruising, high blood sugar, excessive hair growth, and excessive sweating). Inform your doctor about any known intolerance to specific sugars before taking this medicine as it contains lactose.
Uses of Vfend 50mg Tablet
- Invasive Aspergillosis
- Candidemia in non-neutropenic patients
- Esophageal candidiasis
- Fungal infections (caused by Scedosporium apiospermum, Fusarium spp., and Fusarium solani)
- Candida infections
- Fungal infections in high-risk bone marrow transplant patients
Therapeutic Effects of Vfend 50mg Tablet
The mechanism of action of the Vfend 50mg tablet involves inhibiting the production of ergosterol, disrupting fungal cell membranes, and inducing cell death, ultimately eradicating the infection.
Interaction of Vfend 50mg Tablet with other drugs
Notify your doctor of any prescribed medications, over-the-counter drugs, nutritional or vitamin supplements, and herbal products you are currently taking or have taken before starting the treatment. Some medications may interact with Vfend 50mg tablet, leading to potential undesirable side effects.
More Information about Vfend 50mg Tablet
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Do not store above 30°C.
- Always check the expiry date before consuming it.
How to consume Vfend 50mg Tablet
Follow your doctor’s instructions when taking the Vfend 50mg tablet. Typically, the tablets can be taken with or without food. Refrain from crushing, chewing, or opening the medication. The appropriate dosage and duration will be determined by your physician, considering factors such as age, body weight, and the specific disease condition. Only discontinue the tablets if your doctor instructs you to do so.
Safety Advices for Vfend 50mg Tablet
Pregnancy
Avoid using the 50mg tablet during pregnancy unless specifically instructed by your doctor. Employ effective contraception and promptly inform your doctor if you discover you are pregnant while on the medication.
Breast Feeding
There is limited information regarding the use of Vfend 50mg tablet during breastfeeding. Therefore, before initiating the treatment, inform your doctor if you are breastfeeding. For further details, consult your doctor.
Liver
Exercise caution when using Vfend 50mg tablet in patients with liver issues. Prior to commencing the treatment, inform your doctor about any pre-existing liver conditions. Dose adjustment may be necessary in such cases, and your doctor will monitor the functions of your liver.
Alcohol
It is unsafe to consume alcohol while taking Vfend 50mg tablet.
Driving
The use of Vfend 50mg tablet may impact the ability to drive or operate machinery due to potential side effects such as blurred vision or increased sensitivity to light.
Side Effects of Vfend 50MG Tab
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Rash
- Visual disturbances
- Liver problems
- Arrhythmias and QT prolongation
- Jaundice (Changes in blood tests of liver function)
- Pancreatitis (inflammation of the pancreas)
Common
- Fever, headache
- Nausea, vomiting, diarrhea
- Swelling of the extremities
- Itchiness and rashes
- Sinusitis
- Pain in the stomach, back
- Blood in urine
- Seizures
- Low BP
- Hair loss
- Low levels of glucose, sodium, potassium, WBC, platelet
- Neutrophil counts in the blood.
Word of Advice
Exercise caution when liver and heart patients use Vfend 50mg tablet and inform their doctor of all underlying medical conditions. Refrain from stopping the medication unless advised by your doctor, and avoid doubling the dose to compensate for a missed one.
Unless directed by your doctor, do not use this medication during pregnancy or while breastfeeding while taking Vfend 50mg tablet. Report any serious side effects to your doctor, who will guide you on the necessity of dose adjustments. For additional information, contact your doctor.
FAQs
Q 1. How does Vfend 50mg tablet work?
Vfend 50mg tablet inhibits ergosterol production, disrupting fungal cell membranes and leading to cell death, thereby eliminating the infection and relieving symptoms.
Q 2. Can you take Vfend 50mg tablet when pregnant?
Consult your medical professional regarding the use of Vfend 50mg tablet during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it’s necessary
Q 3. How long does Vfend 50mg tablet take to work?
The effectiveness of Vfend 50mg tablet can vary among individuals and depends on the specific fungal infection being treated. While some people may experience symptom improvement within a few days, others may require several weeks to see noticeable results. Discuss with your doctor for more information.
Q 4. What should I do if I miss a dose of Vfend 50mg tablet?
If you miss a capsule dose, take it as soon as possible. However, if it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose the Vfend 50mg tablet.
Fact Box of Vfend 50mg Tablet
Molecule Name: Voriconazole
Pharmacological class: Fungal ergosterol synthesis inhibitor
Therapeutic class: Antifungal drug
Indications: 1. Invasive Aspergillosis 2. Candidemia in non-neutropenic patients 3. Esophageal candidiasis 4. Fungal infections (caused by Scedosporium apiospermum, Fusarium spp., and Fusarium solani) 5. Candida infections 6. Fungal infections in high-risk bone marrow transplant patients |
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