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Introduction to Spexib 150mg Capsule
Spexib 150mg capsule contains the active ingredient Ceritinib, an antineoplastic drug classified as a tyrosine kinase inhibitor. This medication is prescribed for adult patients with a specific type of lung cancer known as Anaplastic Lymphoma Kinase (ALK) positive non-small cell lung cancer (NSCLC). Avoid taking this capsule if you are allergic to Ceritinib or any other components of this medicine. Before starting treatment, inform your physician if you have a history of kidney, lung, liver, or pancreas issues, or if you have diabetes.
Be sure to notify your doctor if you have a heart condition, a prolonged QT interval (an abnormality in the heart’s electrical activity), or if you are currently taking steroids. While on Spexib 150mg, your doctor may conduct regular blood tests to monitor liver, blood, and pancreas function—every two weeks during the first three months of treatment, and monthly thereafter. Additionally, avoid consuming grapefruit or grapefruit juice, as it can increase the levels of the medication in your blood.
Uses of Spexib 150mg Capsule
- Anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC)
Therapeutic Effects of Spexib 150mg Capsule
ALK gene is a fusion protein that signals the cells to grow and divide uncontrollably, leading to the development of cancer. Spexib 150mg works by binding to the ALK protein, preventing its activity and stopping the growth and spread of cancer cells.
Interaction of Spexib 150mg Capsule with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications such as ritonavir, Antifungal, antibiotics, anti-epileptics, and other medications may interact with Spexib 150mg and reduce its effectiveness by causing undesirable side effects.
More Information about Spexib 150mg Capsule
- Do not store above 30˚C
- Keep it in the original container
- Keep this medicine out of the sight and reach of children.
How to consume Spexib 150mg Capsule
Take the capsules at about the same time each day. The recommended dose is 450mg, taken once daily with food. Swallow the capsules whole and do not crush, chew, dissolve, or open the capsules. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advices
Pregnancy
This medicine is unsafe for use during pregnancy. Hence, check with your physician if you are pregnant or think you might be pregnant before taking this medicine. Use effective contraception methods.
Breast Feeding
It is unsafe to breastfeed while taking Spexib 150mg because it can cause toxicity to the baby. Consult your physician for more information.
Lungs
Inform your physician about any underlying lung disorders before taking Spexib 150mg, as this medication should be used with caution in such conditions. Consult your physician before taking this medicine. Notify your doctor if you experience any lung-related symptoms, such as difficulty breathing.
Liver
Inform your physician about any underlying liver disorders before taking Spexib 150mg, as this medication should be used with caution in liver disease patients. Consult your physician before taking this medicine.
Alcohol
It is unknown whether it is safe to consume alcohol with Spexib 150mg. Please consult your doctor for more information.
Driving
It is unsafe to drive while taking Spexib 150mg because this medicine might cause vision problems and tiredness, so avoid driving and operating machinery during this treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Increase urination
- Irregular heartbeat
- Cough with or without mucus
- Fever Chest pain
- Difficulty in breathing or swallowing
- Swelling in the face, lips, tongue or throat
- Severe itching in the skin with bumps or red rash
- Right side abdomen pain
- Bleeding and Bruises
Common
- Decreased appetite
- Anemia
- The lower level of phosphate
- Diarrhea
- Nausea
- Vomiting
- Stomach ache
- Constipation
- Skin rash
Word of Advice
Your doctor may perform an electrocardiogram to check your heart functioning level. It is important to take Spexib 150mg daily as long as your doctor prescribes it. Use highly effective contraception during and after the treatment for three months. Your doctor may conduct a blood test every two weeks of the first three months to monitor liver, blood, and pancreas function. If you vomit after taking the capsule, do not take another one. Notify your doctor if you experience any side effect symptoms, as your doctor may change the dosage of this medicine or give additional medicine to reduce the effect of the side effects.
FAQs
Q 1. Can Spexib 150mg cause liver damage?
Spexib 150mg may cause liver function abnormalities, indicating liver damage. It is important to have regular blood tests to monitor your liver function while taking this medicine. If you experience symptoms of liver damage, such as jaundice or abdominal pain, you should contact your doctor immediately.
Q 2. Does Spexib 150mg cure cancer?
Spexib 150mg is not a cure for cancer, but it can help to slow down or stop the growth and spread of cancer cells, improving the overall survival and quality of life of patients with certain types of cancer.
Q 3. Who should not take Spexib 150mg?
Spexib 150mg should not be taken by pregnant or breastfeeding women or by people with certain medical conditions such as severe liver or lung, heart disease, a history of pancreatitis, diabetes, or a prolonged QT interval.
Fact Box
Molecule name: Ceritinib
Pharmacological class: Anaplastic Lymphoma Kinase Inhibitors
Therapeutic class: Antineoplastic drug
Indication: Anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC)
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