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Introduction to Simulect 20mg Injection
Simulect 20mg injection contains the active ingredient Basiliximab, classified as a monoclonal antibody and belonging to the medication class known as immunosuppressants. It serves to prevent the rejection of kidney transplants. Typically administered within the initial 4 to 6 weeks post-transplant, it is suitable for use in adults, adolescents, and children. Upon transplant, the body’s immune system identifies the new organ as foreign and endeavors to reject it. This medication functions by inhibiting the immune cells responsible for attacking the transplanted organs. Following treatment, your doctor may prescribe additional medications such as Ciclosporin and Corticosteroids to safeguard the new kidney.
If you have allergies to Basiliximab or any of its components, or if you are pregnant or breastfeeding, refrain from using Simulect 20mg injection. Prior to commencing treatment, disclose to your doctor if you’ve previously undergone a transplant that failed shortly afterward or if you’ve had an unsuccessful transplant surgery. Before receiving any vaccines, seek advice from your doctor. Notify your physician if you are pregnant or planning to conceive. Implement effective contraception to prevent pregnancy during therapy and for up to 4 months following the final dose. Avoid breastfeeding for up to four months after the second dose. Consult your doctor regarding any additional fertility concerns.
Uses of Simulect 20mg Injection
Prevents rejection of kidney transplant
Therapeutic Effects of Simulect 20mg Injection
Simulect 20mg injection is a monoclonal antibody that specifically targets and inhibits the activation of the interleukin-2 receptor alpha (IL-2Rα) receptor. By doing so, it diminishes the activation and proliferation of immune cells, notably T lymphocytes (T cells), which play a significant role in organ rejection.
Interaction of Simulect 20mg Injection with other drugs
Prior to treatment, ensure to inform your doctor about all prescribed medications, over-the-counter drugs, nutritional or vitamin supplements, and herbal products you are currently taking or have taken in the past. Some medications may interact with Simulect 20mg injection, potentially resulting in undesirable side effects.
More Information about Simulect 20mg Injection
- Keep out of sight and reach of pets and children
- Store in a refrigerator at a temperature around 2°C – 8°C.
How to consume Simulect 20mg Injection
A healthcare professional will administer Simulect 20mg injection to you in a hospital environment. Typically, it is delivered as an intravenous injection directly into a vein. Your doctor will determine the appropriate dosage, route of administration, and frequency based on your specific disease condition and other relevant factors.
Safety Advices for Simulect 20mg Injection
Pregnancy
Simulect 20mg injection is unsafe during pregnancy as it may harm the unborn baby. Report to your medical professional if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment. Use effective contraception during and after the last dose for up to four months.
Breast Feeding
Taking Simulect 20mg injection while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the second dose. Therefore, talk with your doctor to get more information.
Liver
It is unknown whether Simulect 20mg injection is safe for patients with liver problems. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any liver-related symptoms.
Alcohol
It is unknown whether consuming alcohol while taking a Simulect 20mg injection tablet is safe. Please speak with your physician.
Driving
Simulect 20mg injection does not affect the driving ability.
Side Effects of Simulect 20mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (swelling of face, tongue, or lips, difficulty in breathing, fast heartbeat, dizziness, decreased urine output).
Common
- Constipation
- Nausea
- Diarrhea
- Sudden weight gain
- Overgrowth of normal hair
- Infections
- High blood pressure
- Running nose
Word of Advice
Simulect 20mg injection is given as an injection into the veins by a healthcare provider only. Inform your medical professional if you are above 65 years older because this medicine is not studied in such conditions. Do not stop the medicine until your doctor advises. Notify your doctor if you experience any serious side effects. Your doctor may change your dose or stop the treatment. Your medical professional will inform you if you need any dose adjustments. Children under 35 kg will receive a dose lower than what is typically administered to adults. Contact your doctor for more information.
FAQs
Q 1. How can I manage diarrhea while taking Simulect 20mg injection?
If you experience diarrhea while taking Simulect 20mg injection, stay hydrated by drinking plenty of fluids. Your medical professional may also recommend over-the-counter or prescription medications to help manage your diarrhea. If your diarrhea is severe or persistent, you should contact your doctor.
Q 2. How long should I take Simulect 20mg injection?
Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking Simulect 20mg injection if your doctor advises you to stop.
Q 3. How should Simulect 20mg injection be used?
A well-trained physician or nurse should always inject intravenous injection into the patient. Kindly do not self-administer the Simulect 20mg injection.
Fact Box of Simulect 20mg Injection
Molecule Name: Basiliximab
Pharmacological class: Monoclonal antibody
Therapeutic class: Immunosuppressant
Indications: Prevents rejection of kidney transplant
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