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Introduction to Rybrevant 350mg Injection
The injection Rybrevant 350mg comprises the active ingredient Amivantamab, classified as an antineoplastic drug within the bispecific antibodies category. It is prescribed for the treatment of non-small cell lung cancer (NSCLC) that has metastasized and exhibits specific alterations in the EGFR gene. This medication is employed in cases where surgical removal is not feasible, and the condition has progressed despite or after treatment with other anticancer drugs.
Avoid taking this injection if you are allergic to amivantamab or any other components of this medication. Prior to starting the therapy, inform your physician about any history of lung inflammation or other lung conditions. Promptly report to your physician if you experience sudden difficulty in breathing, cough, or fever, as these symptoms may indicate lung inflammation. Rybrevant 350mg injection is not recommended for individuals below 18 years of age.
Disclose any existing kidney problems, as well as liver or lung issues, to your physician before commencing the therapy. Common side effects of Rybrevant 350mg injection include rash, nail inflammation, musculoskeletal pain, shortness of breath, nausea, fatigue, swelling, inflamed and sore mouth, cough, constipation, and vomiting. It is crucial to use effective contraception during the treatment as this medicine may harm the fetus.
Uses of Rybrevant 350mg Injection
Non-small cell lung cancer (NSCLC)
Therapeutic Effects of Rybrevant 350mg Injection
Rybrevant 350mg injection is a bispecific antibody targeting the epidermal growth factor receptor (EGFR) and mesenchymal-epithelial transition factor (MET). Specifically designed to identify and bind to specific targets in the body, it focuses on two proteins present in cancer cells. The mechanism involves attaching to these proteins, potentially slowing or halting the growth of lung cancer and reducing the size of the tumor.
Interaction of Rybrevant 350mg Injection with other drugs
Notify your healthcare provider of all the medications you are currently using, including prescription drugs, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, as well as herbal products. Some medications have the potential to interact with Rybrevant 350mg injection, diminishing its effectiveness and leading to undesirable side effects.
More Information about Rybrevant 350mg Injection
- Store Rybrevant 350mg injection in the refrigerator (2°C to 8°C)
- Do not freeze
- keep the injection away from the reach of children and pets.
- If you have missed any dosing appointments, inform your doctor and schedule immediately.
How to consume Rybrevant 350mg Injection
A healthcare professional trained in cancer chemotherapy will administer Rybrevant 350mg injection in a hospital or clinic setting. The medication is delivered as an intravenous infusion drip, gradually introduced into your vein over several hours. It is important not to self-administer the injection. The specific dose and duration of the treatment will be determined by your doctor, taking into consideration factors such as the severity of your disease, body weight, and other relevant considerations.
Safety Advices for Rybrevant 350mg Injection
Pregnancy
Rybrevant 350mg injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 3 months after your last dose is necessary.
Breast Feeding
Breastfeeding is not recommended in patients taking Rybrevant 350mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Liver
It is unknown whether Rybrevant 350mg injection can be used in patients with liver disorders. Consult your doctor if you have any liver problems before starting the treatment.
Alcohol
It is unknown whether consuming alcohol is safe during the treatment with Rybrevant 350mg injection. Inform your doctor if you are a chronic drinker.
Driving
Rybrevant 350mg injection does not affect the ability to drive. If you feel tired or dizzy after taking this medicine, do not drive and consult your doctor for more advice.
Side Effects of Rybrevant 350mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Swelling in the face, hands, and feet
- Inflammation in the nails
- Constipation
- Nausea, vomiting
- Inflamed and sore mouth
- Musculoskeletal pain
- Cough
- Shortness of breath
- Tiredness
Serious
- Severe rashes in the skin
- Eye pain and infection
- Inflammation of the lungs
- Infusion reactions
Word of Advice
To minimize skin issues, restrict sun exposure throughout the treatment period and for 2 months afterward. Wear protective clothing, regularly apply sunscreen and alcohol-free moisturizers to your skin and nails while using this medication. If you experience eye pain or vision problems, contact your doctor or nurse promptly. Prior to using contact lenses while on this medication, consult your doctor. Refrain from breastfeeding during the treatment and for 3 months after the final dose. Your doctor may recommend specific tests to assess the effectiveness of the therapy.
FAQs
Q 1. What are the infusion reactions that might happen during Rybrevant 350mg infusion?
Allergic reactions like itching. Swelling in your face or hands, tingling in mouth or throat, chest tightness, difficulty in breathing, fever, chills, cough, sore throat, body aches, unusual bleeding, bruising, or weakness should be informed to your doctor immediately.
Q 2. How long should I have to take Rybrevant 350mg injection?
Rybrevant 350mg injection is given as a cycle therapy. Your doctor will decide the dose and duration of the therapy based on your disease severity and condition.
Q 3. How long does Rybrevant 350mg infusion take?
Your first dose (the infusion on Day 1 and Day 2) can take about 4 to 6 hours. Infusions can get shorter starting on Week 2, and can take about 2 to 4 hours. Your doctor will decide the infusion rate based on your disease condition and other factors.
Q 4. What are the eye problems that may occur while taking Rybrevant 350mg injection?
Eye pain, dry eyes, eye redness, blurred vision, changes in the vision, itchy eyes, excessive tearing, sensitivity to light are the eye problems that may occur with this treatment. Inform your physician if you face any of the symptoms.
Fact Box of Rybrevant 350mg Injection
Molecule name: Amivantamab
Pharmacological class:
EGFR inhibitor & MET tyrosine kinase inhibitors
Therapeutic class: Antineoplastics
Indications:
Treat non small cell lung cancer (NSCLC)
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