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Introduction to Regonat 40mg Tablet
Regonat 40 mg tablets consist of regorafenib, an active substance utilized in cancer treatment to impede the proliferation of cancer cells. These tablets are effective against colon or rectal cancer, specific types of stomach and bowel cancers, as well as liver cancer. Before using this medication, consult your doctor, especially if you have liver issues, a history of bleeding problems, severe gastrointestinal issues, heart conditions, or high blood pressure. Avoid taking this medicine if you are allergic to regorafenib.
Uses of Regonat 40mg Tablet
Regonat 40 mg tablet is used in the treatment of:
- Colorectal cancer has started to spread to other parts of the body
- Gastrointestinal stromal tumors (GIST) (a type of stomach and bowel cancer)
- Liver cancer in adult patients who have already undergone treatment with Sorafenib
Therapeutic Effects of Regonat 40mg Tablet
Regonat 40 mg tablets function by decelerating the proliferation and dissemination of cancer cells while interrupting their blood supply.
Interaction of Regonat 40mg Tablet with other drugs
Before starting treatment, disclose to your doctor all prescribed medications, over-the-counter drugs, dietary supplements, vitamins, and herbal products you currently take or have taken previously. Some medications might interact with Nublex 40 mg tablets, leading to unwanted side effects. Using this tablet alongside CYP3A4 inhibitors such as oral ketoconazole and similar drugs could result in interactions.
More Information about Regonat 40mg Tablet
- Keep Regonat 40 mg tablet out of sight and reach of children. Do not use it after the expiration date.
How to consume Regonat 40mg Tablet
Adhere strictly to the prescribed dosage provided by your doctor. Refrain from crushing, chewing, or breaking the Regonat 40 mg tablet; swallow it whole with water. It’s recommended to take the tablet alongside food.
Safety Advices for Regonat 40mg Tablet
Pregnancy
Regonat 40 mg tablet is not safe to be used during pregnancy. Consult with your doctor for advice.
Breast Feeding
It is not recommended to breastfeed while taking Regonat 40 mg tablets. Consult with your doctor for advice.
Lungs
Regonat 40 mg tablet should be used with caution in patients with a history of lung disease. Please consult your doctor for more advice.
Liver
Regonat 40 mg tablets should be used cautiously in patients with liver diseases. Consult with your doctor for advice.
Alcohol
It is unknown whether it is safe to consume alcohol with Regonat 40 mg Tablet. Please consult your doctor.
Driving
It is not known whether Regonat 40 mg Tablet alters the ability to drive. Do not drive if you experience symptoms affecting your ability to concentrate and react.
Side Effects of Regonat 40mg Tablet
Medications can lead to side effects, which are unwanted symptoms. However, not everyone experiences these side effects despite their presence in all medications.
Serious:
- Allergic reaction
- Severe liver problems
- Bleeding
- Gastrointestinal perforation
- Infections
- Heart attack and severe chest pain
- Severely high blood pressure
- Skin eruptions
- Pancreatitis
- Skin cancers
- Confusion, Seizures, headaches, and vision loss with or without high blood pressure
- Stevens-Johnson syndrome
- Skin detachment
- Enlargement of a blood vessel or a tear in a blood vessel
Common:
- Reduced number of white blood cells
- Hypothyroidism
- Lowered levels of phosphate, potassium, calcium, sodium, or magnesium
- Elevated level of uric acid in the blood
- Dehydration
- Headache and tremors
- Disorder of the nerves that causes numbness, tingling, weakness, or pain (peripheral neuropathy)
- Changes in taste, dry mouth
- Heartburn
- Gastroenteritis (inflammation and infection of the stomach)
- Hair loss (alopecia)
- Dry skin
- Rashes
- Muscle spasms
- Protein in urine
- Abnormal blood clotting condition
Word of Advice
Consult the doctor if the patient has liver disorders, infections, bleeding issues, gastrointestinal concerns, chest pain, heart conditions, high blood pressure, persistent headaches, seizures, or recent or upcoming surgical procedures before starting this medication. It’s not advisable for adolescents or children. Steer clear of grapefruit juice while on this medication as it can impact its effectiveness. Avoid this medicine if planning pregnancy, during pregnancy, or breastfeeding due to potential harm to the developing baby.
FAQs
Q 1. Is Regonat 40 mg tablets chemotherapy?
Regonat 40 mg tablets are used as chemotherapy to treat cancer of the stomach, colon, or rectal when other medications and treatments become ineffective.
Q 2. How are Regonat 40 mg tablets taken?
It is taken as prescribed by the doctor. It is taken once daily along with the food at a fixed time and does not stop this medication without the proper advice of the doctor.
Q 3. Can I take grapefruit juice while taking a Regonat 40 mg tablet?
No, patients are advised not to take grapefruit juice while taking this medication as it decreases the effectiveness of the medicine.
Q 4. Is it safe to use Regonat 40 mg tablet during pregnancy?
It is unsafe to use this medication if the patient is planning for pregnancy or during pregnancy as it causes harmful effects on the developing baby.
Q 5. What is the use of Regonat 40 mg tablet?
It is used to treat colon cancer, rectal cancer, liver cancer, and gastrointestinal stromal tumors (GIST) (a type of cancer of the stomach and bowel).
Fact Box of Neomol 80mg Injection
Molecule name: Regorafenib
Pharmacological class:
Anti-Neoplastics
Therapeutic class: Tyrosine kinase inhibitor
Indications:
- Colorectal cancer
- Gastrointestinal stromal tumors (GIST) (a type of stomach and bowel cancer)
- Liver cancer
References
- Bayer AG; Electronic Medicines Compendium; [Revised:2019] [Accessed:29/Apr:2021] https://www.medicines.org.uk/emc/files/pil.1263.pdf
- TJ Ettrich et al; Regorafenib; [Revised:2014] [Accessed:29/Apr/2021] https://pubmed.ncbi.nlm.nih.gov/24756792/
- Dirk Strumberg; Regorafenib for cancer; [Revised:2012] [Accessed:29/Apr/2021] https://pubmed.ncbi.nlm.nih.gov/22577890/
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