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Introduction to Leucorin 15mg Tablet
Leucorin 15mg Tablet is an anticancer medication classified as a detoxifying agent, with the active ingredient Calcium Leucovorin (also known as Calcium Folinate). It is primarily used to treat megaloblastic anemia, a condition characterized by the presence of large, immature, and dysfunctional red blood cells (megaloblasts) in the bone marrow. Additionally, it enhances the effectiveness of 5-fluorouracil in the treatment of certain cancers by increasing the drug’s efficacy while reducing its toxicity. Leucorin can also be used to treat overdoses of folic acid antagonists and to protect healthy cells from the toxic effects of chemotherapy by “rescuing” them.
This medication is contraindicated in patients with hypersensitivity to any of its components. Allergic reactions may occur in some individuals, with symptoms such as itching, difficulty breathing, facial or throat swelling, and a rapid heartbeat. If any of these symptoms are experienced, seek medical attention immediately. It’s important to avoid excessive doses of Leucorin 15mg Tablet, as this may diminish the antitumor effects of methotrexate, particularly in CNS tumors where calcium folinate can accumulate after repeated courses.
Uses of Leucorin 15mg Tablet
- Treatment of Megaloblastic Anaemia
- Reduce the toxicity of methotrexate
- Overdose of Folic Acid Antagonists
- Enhance the effectiveness of 5-fluorouracil
Therapeutic Effects of Leucorin 15mg Tablet
Leucorin 15mg tablet works by enhancing the effects of folic acid in the body. It is taken up by cells through a specific transporter protein and converted into the active form of folic acid, which can be used by cells to produce DNA and form new cells. This drug is given after methotrexate to help rescue normal cells that require folate for their growth.
Interaction of Leucorin 15mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with leucorin 15mg tablet and reduce effectiveness by causing undesirable side effects.
More Information about Leucorin 15mg Tablet
- Keep it out of reach from children and pets.
How to consume Leucorin 15mg Tablet
Take leucorin 15mg tablet exactly as prescribed by your doctor. Do not self-administer this medicine. Do not crush or chew the tablet. Do not exceed the recommended dosage. The dose of the leucorin 15mg tablet will be decided by your doctor based on your disease condition and other factors.
Safety Advices
Pregnancy
It is not known whether leucorin 15mg tablet can cause foetal harm, when administered to pregnant women. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Breast Feeding
It is not known if leucorin 15mg tablet passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.
Lungs
It is not known if leucorin 15mg tablet passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.
Liver
Inform your doctor if you have any liver problems before taking leucorin 15mg tablet. Regular monitoring of liver function tests is recommended.
Alcohol
It is unknown whether consuming alcohol interacts with the leucorin 15mg tablet. Please consult your doctor for more advice.
Driving
It is completely safe to drive after taking the leucorin 15mg tablet.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Reduced number of blood cells
- Inflammation in the lining of mouth and intestine
- Severe allergic reactions
Common
- Nausea, vomiting, severe diarrhoea
- Redness and swelling of palms of hands and soles of feet
Word of Advice
Special care is needed if you are elderly and you are about to receive any fluorouracil treatment and leucorin 15mg tablet at the same time in case you undergo radiotherapy or stomach trouble. Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
FAQs
Q 1. What are the special precautions I should be aware of before starting treatment with leucorin 15mg tablet?
Leucorin 15mg tablet is eliminated from the body primarily through the kidneys. Patients with impaired kidney function may need a lower dose or less frequent dosing of this drug.
Q 2. Can leucorin 15mg tablet be used in combination with other drugs?
Yes, leucorin 15mg tablet is used as an antidote to reduce the toxic effects of methotrexate, a chemotherapy drug that is used to treat certain types of cancer.
Q 3. What does leucorin 15mg tablet do to your body?
Leucorin 15mg tablet works by supplying the body with the necessary folate, which is required for the production of red blood cells, DNA synthesis, and other important cellular functions.
Fact Box
Molecule name: Calcium Leucovorin/Calcium Folinate
Pharmacological class: Detoxifying agents
Therapeutic class: Anti-cancer
Indications:
1.Treatment of Megaloblastic Anaemia
2.Reduce the toxicity of methotrexate
3.Treatment of Overdosage of Folic Acid Antagonists
4.Enhance the effectiveness of 5-fluorouracil
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