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Introduction to Kabanat 60mg Injection
Kabanat 60mg Injection contains the active ingredient cabazitaxel. It is an anticancer medication used in combination with the steroid medicine prednisone or prednisolone to treat hormone-refractory metastatic prostate cancer that has progressed after treatment with other anticancer drugs, including docetaxel. Cancer is characterized by the abnormal and uncontrolled multiplication of cells. Many early-stage prostate cancers require normal levels of testosterone (a male hormone) to grow. In hormone-refractory metastatic prostate cancer, the cancer continues to grow even when testosterone levels are significantly reduced. This medicine should not be used if you have severe liver dysfunction or have recently received a yellow fever vaccine.
The major toxicities of this drug include myelosuppression, neurotoxicity, and allergic reactions, with neutropenia being the most common adverse effect. It is essential to monitor complete blood counts weekly during the first cycle and before each subsequent treatment cycle to adjust the dose if necessary. Patients receiving this medicine should avoid live attenuated vaccines; instead, killed or inactivated vaccines can be administered.
Uses of Kabanat 60mg Injection
Advanced prostate cancer.
Therapeutic Effects of Kabanat 60mg Injection
This drug is a mitotic inhibitor that disrupts the normal process of cell division by interfering with microtubules, which are essential for forming the cell’s cytoskeleton and pulling apart chromosomes during mitosis. By inhibiting microtubules, the drug prevents cancer cells from dividing properly, ultimately leading to their death.
Interaction of Kabanat 60mg Injection with other drugs
Inform your healthcare provider about all the medicines you are taking, including prescription medications, over-the-counter drugs, nutritional supplements, vitamins, and herbal products. Certain medications can interact with Kabanat 60mg Injection, potentially reducing its effectiveness or causing undesirable side effects.
More Information about Kabanat 60mg Injection
- Store Kabanat 60mg Injection in the original package at room temperature (30°C).
- Do not refrigerate.
How to consume Kabanat 60mg Injection
A healthcare professional will administer this medicine to you in a hospital setting. The recommended dose is 25 mg, given as an intravenous infusion over one hour every three weeks, in combination with 10 mg of oral prednisone taken daily. The dose may be adjusted based on individual factors such as age, body weight, and other medical conditions.
Safety Advices for Kabanat 60mg Injection
Pregnancy
It is unsafe to use during pregnancy whether Kabanat 60mg Injection can be taken during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Breast Feeding
It is unsafe to breastfeed during the treatment with this Kabanat 60mg Injection because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Lungs
It is unknown whether Kabanat 60mg Injection can be used for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
It is unknown whether Kabanat 60mg Injection can be used for patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this drug.
Alcohol
It is unknown whether consuming alcohol interacts with the Kabanat 60mg Injection. Please consult your doctor for more advice.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking the Kabanat 60mg Injection because it contains a small amount of alcohol which may cause dizziness and impair your concentration.
Side Effects of Kabanat 60mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Low white blood cells
- Infection (fever, cough, muscle aches, burning on urination)
- Severe allergic reactions (rash, itching, breathing problems, swelling of face, chest, or throat tightness)
- Kidney damage
- Severe stomach pain
Common
- Low red blood cell count
- Low blood platelet count
- Constipation
- Back pain, joint pain
- Decreased appetite
- Hair loss
- Numbness, burning, tingling, or decreased sensation in your feet or hands
- Taste change
- Headache, dizziness
- Inflammation of the mouth
- Blood in urine
Word of Advice
When you have diarrhea, drink at least two liters of fluids daily. Avoid milk, dairy products, high-fiber foods, and spicy foods. Rinsing your mouth with an alcohol-free mouthwash or salt water may help reduce the risk of infections like mouth ulcers. This drug can lower your white blood cell count, increasing the risk of infection, so avoid crowds and sick individuals, and wash your hands after using the toilet.
You must not become pregnant during treatment and should use effective contraception. If you become pregnant, inform your doctor immediately. This drug may cause dizziness, so avoid driving, operating machinery, or engaging in activities requiring alertness until you can do so safely. If you have a history of alcohol addiction, liver disease, or epilepsy, consult your doctor before taking this medicine.
FAQs
Q 1. Why is prednisone given with Kabanat 60mg Injection?
This drug is designed to kill cancer cells by decreasing their ability to divide into more cells. Prednisone is taken with Kabanat 60mg Injection as part of the chemotherapy regimen to possibly slow the growth of cancer cells and reduce side effects from chemotherapy.
Q 2. How does Kabanat 60mg Injection work?
This drug shrinks tumors by attacking rapidly dividing cells, including cancer cells, so they can no longer grow and divide.
Q 3. Who should not use Kabanat 60mg Injection?
Kabanat 60mg Injection is not indicated for children and adolescents under the age of 18. It should not be used in people who are allergic to this drug, as well as pregnant or breastfeeding women.
Fact Box of Kabanat 60mg Injection
Molecule name: Cabazitaxel
Pharmacological class: Mitotic inhibitors
Therapeutic class: Anticancer
Indications:
Advanced prostate cancer
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