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Introduction to Grafalon 100mg Injection
Grafalon 100mg injection comprises Human rabbit anti-T cell immunoglobulin as its active components. This medication is employed in the treatment of severe graft-versus-host disease (GvHD). GvHD occurs when the immune cells (T cells) from the donor target and attack the recipient’s body cells, perceiving them as foreign. This condition can impact various parts of the body, with the skin, liver, gut, and lungs being the most commonly affected. It is important to note that if you have experienced a severe allergic reaction to this medication or other monoclonal antibodies, it is contraindicated for use.
If you suffer from severe kidney or liver disease, it is advisable to avoid Grafalon 100mg injection as it may exacerbate your condition. This medication has the ability to penetrate the blood-brain barrier, potentially leading to issues in the brain, and should be avoided if you have active central nervous system (CNS) disease to prevent any worsening of your condition. Additionally, Grafalon can traverse the placenta and pose a risk to the fetus, so it is contraindicated during pregnancy or breastfeeding.
While generally considered safe for older adults and children, it is crucial to discuss potential risks and benefits with your doctor before initiating Grafalon 100mg injection therapy.
Uses of Grafalon 100mg Injection
Grafalon 100mg injection is used in the following:
- Graft-versus-host disease (GvHD)
Therapeutic Effects of Grafalon 100mg Injection
Grafalon 100mg injection works by reducing T cells, the cells responsible for attacking the body’s tissues in graft-versus-host disease (GvHD). This is achieved through the binding of Grafalon to the surface of T cells, activating the immune system to eliminate them. Additionally, it has the capacity to impede the development of T cells from the outset.
Interaction of Grafalon 100mg Injection with other drugs
Notify your doctor about all the medications you are taking, including prescriptions, over-the-counter drugs, nutritional or vitamin supplements, and herbal products. Some medications may interact with Grafalon 100mg injection, potentially diminishing its effectiveness and leading to undesirable side effects.
More Information about Grafalon 100mg Injection
- Stored at room temperature from 2-8°C.
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Grafalon 100mg Injection
Administration of Grafalon 100mg injection can occur through intravenous (IV) infusion or intramuscular (IM) injection. The intravenous route is the predominant method, chosen by the doctor based on the patient’s requirements and preferences.
Safety Advices for Grafalon 100mg Injection
Pregnancy
Grafalon 100mg injection is unsafe for pregnant women as it can cross the placenta and harm the fetus.
Breast Feeding
Grafalon 100mg injection can pass into breast milk and may harm the baby, so it is safe for breastfeeding women.
Liver
Individuals with liver conditions should consult with their healthcare provider before taking Grafalon 100mg injection.
Alcohol
Alcohol can increase the risk of side effects from Grafalon 100mg injection, such as low blood counts and infections. It is safe to take alcohol while taking it.
Driving
Grafalon 100mg injection can cause side effects, such as fatigue and dizziness. These side effects can affect your ability to drive. It is important to talk to your doctor about whether it is safe for you to drive while taking
Side Effects of Grafalon 100mg Injection
Grafalon 100mg injection causes some side effects like all medications, although not everyone will experience them.
Serious
- Allergic reaction
- Low blood counts
- Infection
- Kidney problems
- Liver problems
- Pneumonitis
- Pulmonary edema
- Thrombosis
- Death
Common
- Fever
- Chills
- Nausea
- Vomiting
- Diarrhea
- Headache
- Muscle pain
- Fatigue
- Rash
- Itching
Word of Advice
Before initiating Grafalon 100mg injection, it is crucial to discuss the associated risks and benefits with your doctor. This medication may lead to low blood counts, infections, kidney problems, liver problems, pneumonitis, pulmonary edema, thrombosis, and even death. Regular monitoring of blood counts is essential to detect any issues early, allowing your doctor to take corrective measures.
Taking precautions against infection is vital, given that Grafalon can weaken the immune system. This involves practicing frequent handwashing, avoiding contact with sick individuals, and receiving vaccinations against common infections.
If you experience symptoms such as hives, itching, rash, shortness of breath, swelling of the face, tongue, or throat, and difficulty breathing, seek medical attention promptly.
FAQs
Q 1. How long does Grafalon 100mg injection treatment last?
The length of Grafalon 100mg injection treatment depends on the condition being treated. It can range from a few days to several weeks.
Q 2. What should I do if I experience side effects from Grafalon 100mg injection?
If you experience any side effects from Grafalon 100mg injection , you should tell your doctor immediately.
Q 3. What are the long-term risks of Grafalon 100mg injection?
The long-term risks of Grafalon 100mg injection are not well known. However, some concern is that it may increase the risk of developing autoimmune diseases.
Q 4. How long does Grafalon 100mg injection take to start working?
The time it takes for Grafalon 100mg injection to start working varies depending on the individual. In some cases, it may start working within a few days. In other cases, it may take several weeks.
Fact Box of Grafalon 100mg Injection
Molecule name: Human rabbit anti-T cell immunoglobulin
Pharmacological class: Monoclonal antibody
Therapeutic class: Immunomodulator
Indications:
Graft-versus-host disease (GvHD)
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