Introduction to Duovir Tablet
Duovir Tablet is a combination medication comprising the active ingredients Lamivudine and Zidovudine. It is employed in the treatment of HIV-1 infection in conjunction with other medications. The human immunodeficiency virus (HIV-1) specifically attacks and destroys immune system cells, leading to a diminished ability of the body to combat infections, and in severe cases, it can result in death.
Individuals with neutropenia (low white blood cells) or anemia (low red blood cells) should avoid using zidovudine or lamivudine. Inform your doctor if you have any liver condition, including hepatitis B or C, kidney disease, or if you are overweight. If you experience common side effects like fat loss in the face, arms, and legs, it is advised to discontinue the treatment. Personal items, such as toothbrushes and razors, should not be shared with others. Seek guidance from your doctor regarding appropriate sexual behavior.
Duovir Tablet is primarily eliminated from the body through the kidneys. In cases of impaired kidney function, your healthcare provider may modify the dosage to avoid potential side effects. Regular monitoring of kidney function is crucial throughout the course of treatment. While this medication can be prescribed to children with HIV, the dosages and formulations may vary.
Uses of Duovir Tablet
- Treatment of HIV–1 infection
Therapeutic Effects of Duovir Tablet
Duovir Tablet functions by inhibiting the reverse transcriptase enzyme crucial for HIV replication. This action impedes viral replication, leading to a reduction in the body’s viral load. Consequently, it slows down the progression of HIV infection, preserves immune function, and lowers the risk of developing complications related to AIDS.
Interaction of Duovir Tablet with other drugs
Notify your healthcare provider about all the medications you are taking, including prescriptions, over-the-counter drugs, nutritional or vitamin supplements, and herbal products. Some medications may interact with Duovir Tablet, potentially diminishing its effectiveness and causing undesirable side effects.
More Information about Duovir Tablet
- Store at temprature 20-25°C (68-77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep it in its original packaging until it is ready to be used.
- Keep out of the reach of children and pets.
How to consume Duovir Tablet
Duovir Tablet capsules or tablets are administered orally. Typically, the medication is taken once a day as instructed by your healthcare provider, with or without food. Ensure that you swallow the capsule or tablet whole without crushing or chewing it.
Safety Advices for Duovir Tablet
Pregnancy
Duovir tablets are generally considered safe during pregnancy. However, it is always important to consult a healthcare provider before using any medication during pregnancy.
Breast Feeding
Duovir Tablet is considered safe while breastfeeding.
Liver
People with pre-existing liver disease, such as cirrhosis or hepatitis, should consult a doctor before taking Duovir Tablet.
Alcohol
Alcohol can interact with Duovir Tablet in various ways, including increasing the risk of side effects, decreasing the effectiveness of the medication, or causing other harmful interactions
Driving
Patients should always monitor their response to the Duovir Tablet medication and be cautious when driving or operating machinery if they experience any side effects that may impair their ability to do so safely.
Side Effects of Duovir Tablet
Duovir Tablet cause side effects like all medications, although not everyone will experience them.
Serious:
- Allergic reactions (hives, itching, inflammation of the face, lips, tongue)
- Lactic acidosis (a buildup of lactic acid in the body)
- Hepatotoxicity (liver toxicity)
- Anemia (low levels of red blood cells)
- Neutropenia (low levels of white blood cells)
- Pancreatitis (severe abdominal pain, nausea, and vomiting)
Common:
- Nausea and vomiting
- Headache
- Diarrhea
- Fatigue or tiredness
- Muscle pain or weakness
- Insomnia or sleep disturbances
- Rash or skin reactions
- Loss of appetite
- Abdominal pain or discomfort
- Joint pain
Word of Advice
Consultation with a healthcare provider is essential before using Duovir Tablet. Report any unusual side effects experienced while using this medication to the healthcare provider. Inform the doctor about any pre-existing liver disease, such as hepatitis B or C, kidney disease, or if you are overweight. For pregnant or breastfeeding women, it is crucial to seek the doctor’s advice before using the medication. If there are any health-related questions, it is advisable to consult a healthcare provider.
Fact Box of Duovir Tablet
Molecule name: lamivudine and Zidovudine
Pharmacological class:
Nucleoside Reverse Transcriptase Inhibitors (NRTIs).
Therapeutic class: Anti-viral
Indications:
Treatment of HIV – 1 infection
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