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Introduction to Bucelon 2mg Tablet
Bucelon 2 mg tablet is an anti-cancer (antineoplastic/cytotoxic) chemotherapy drug, specifically an alkyl sulfonate in the class of alkylating agents. It is indicated for the treatment of blood cancers, such as chronic myelogenous leukemia (a type of cancer that leads to an increase in white blood cells). Additionally, it is used to prepare the bone marrow for receiving healthy blood-forming cells (stem cells) from a donor, replacing the patient’s stem cells that have been destroyed by radiation or high doses of chemotherapy.
Chronic myelogenous leukemia is a rare type of cancer that affects the bone marrow (the soft, spongy tissue that produces blood cells for the body) and leads to an increase in white blood cell count. Common side effects of Bucelon 2 mg tablets include decreased white blood cells, dizziness, shortness of breath, mouth inflammation, nausea, diarrhea, difficulty sleeping, and fever. It is important to drink plenty of fluids while taking this medication.
Uses of Bucelon 2mg Tablet
- Hematopoietic progenitor cell transplantation
- Chronic myelogenous leukaemia
- Polycythaemia vera (type of cancer that causes increase in red blood cells)
- Thrombocythemia (increased number of platelets in the blood)
- Myelofibrosis (type of blood cancer where scar tissues are formed in bone marrow)
- Hemoglobinopathies (a genetic disorder that produces abnormal haemoglobin)
Therapeutic Effects of Bucelon 2mg Tablet
Bucelon works by disrupting the DNA replication process, which is essential for cell division, thereby inhibiting tumor growth. It causes cytotoxicity by reversibly binding to nucleophilic groups on various cell components. The alkylation of DNA is likely the critical cytotoxic reaction that kills tumor cells, damaging their DNA and RNA and halting their growth and multiplication. Bucelon is often combined with other medications to treat various lymphatic and solid cancers.
Interaction of Bucelon 2mg Tablet with other drugs
Inform your physician about any prescribed medications, over-the-counter drugs, nutritional or vitamin supplements, and herbal products you are currently taking or have taken before starting treatment. Some medications may interact with Bucelon 2 mg tablets, potentially causing side effects.
More Information about Bucelon 2mg Tablet
Store it at room temperature and away from excess heat and moisture. Store at 15° to 25°C (59° to 77°F) in a dry place. Keep it out of sight and reach of children.
How to consume Bucelon 2mg Tablet
Your physician will determine the appropriate dose and duration of Busulfan therapy based on your specific type of blood cancer. Swallow the tablets with plenty of water without breaking, crushing, or chewing them. You can take Busulfan tablets before or after meals. Do not stop the medication unless advised by your doctor. If you miss a dose, do not take a double dose. Instead, inform your physician about the missed dose.
Safety Advices
Pregnancy
unsafe during pregnancy. It may cause fetal harm when administered. If you are pregnant or planning to get pregnant, ask your doctor or pharmacist for advice before taking this medicine. This applies to men and women because the drug may harm your sperm or eggs.
Breast Feeding
If you are breastfeeding or plan to breastfeed your baby, talk to your physician because the drug may secrete in breast milk.
Lungs
It is unknown whether Tablet can be given to patients with lung diseases. Please inform your doctor if you have any lung problems.
Liver
Discuss with your physician before taking this medicine if you have liver problems.
Alcohol
It is not known whether it is safe to consume alcohol with Tablet. Please consult your doctor.
Driving
It is not known whether Tablet alters the ability to drive. Do not drive if you experience symptoms affecting your ability to concentrate and react.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them.
Serious
- Myelosuppression (decreased bone marrow activity)
Common
- Thalassaemia
- Hair loss
- Patches of dark skin
- Blood in urine
- Decrease in the number of blood cells and platelets
- Nausea and vomiting
- Jaundice
- Infertility and sterility
- Pneumonia syndrome
Word of Advice
Inform the doctor if the patient has taken radiotherapy priorly to the treatment. If you have other medical conditions like heart disease, lung, kidney, or liver problems. Tell your doctor if you have gout symptoms (pain and swollen joints caused by uric acid crystals).
FAQs
Q 1. Can Bucelon 2 mg tablets cause infertility?
Yes, bucelon 2 mg tablets can cause infertility in both the men and women because it affects the sperm cells and egg. Consult the doctor before taking this medication.
Q 2. How can a Busulfan 2 mg tablet be taken?
Bucelon 2 mg tablet is taken orally. Swallow the whole tablet with water. If you have missed the dose, inform your physician. Don’t take double the dose.
Q 3. Can bucelon 2 mg be used during pregnancy?
No, it is highly unsafe to use this medication during pregnancy as they can cause harmful effects on the developing fetus.
Fact Box
Molecule Name: Busulfan
Pharmacological class: Alkylating agent - Alkyl sulfonates
Therapeutic class: Anticancer
Indication:
1. Chronic myelogenous leukemia
2. Hematopoietic progenitor cell transplantation
3. Polycythaemia vera
4. Thrombocythemia
5. Myelofibrosis
6. Hemoglobinopathies
7. Congenital metabolic diseases
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