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Introduction to Benzz 180mg Injection
Benzz 180 mg Injection is an antineoplastic medication classified as an alkylating agent, comprising the active ingredient Bendamustine. It is employed in the prevention and treatment of chronic lymphocytic leukemia (a form of cancer affecting the blood and bone marrow), non-Hodgkin’s lymphomas (a type of cancer originating in the lymph system, a component of the immune system), and multiple myelomas (a cancer affecting plasma cells, a subtype of white blood cells).
Common side effects associated with this medication may include headaches, insomnia, fatigue, loss of appetite, and rashes. Additionally, serious side effects such as bone marrow suppression, tumor lysis syndrome, and hepatotoxicity may occur. If these side effects concern you or persist longer than expected, it’s important to inform your healthcare provider. This medication is often combined with rituximab, an immunotherapy drug, to treat various subtypes of non-Hodgkin’s lymphoma, including follicular lymphoma and mantle cell lymphoma. However, there may be an increased risk of certain types of skin cancer (non-melanoma skin cancer) associated with its use. Consult your doctor promptly for further advice.
Treatment should not commence if your white blood cell counts have fallen below specified levels, as determined by your doctor at regular intervals. Avoid using this medication if you are allergic to it. If you are a man planning to father a child, discuss the treatment with your physician, as this injection may reduce sperm production. Typically, this drug is administered as an intravenous infusion lasting 30-60 minutes, usually once every three to four weeks. Inform your physician about all medications, including herbal medicines and supplements, that you have recently taken before receiving Benzz 180 mg Injection. This medication is often combined with rituximab, an immunotherapy drug, to treat various subtypes of non-Hodgkin’s lymphoma, including follicular lymphoma and mantle cell lymphoma. However, there may be an increased risk of certain types of skin cancer (non-melanoma skin cancer) associated with its use. Consult your doctor promptly for further advice.
Uses of Benzz 180mg Injection
- Chronic lymphocytic leukaemia.
- Non-Hodgkin’s lymphomas
- Multiple myeloma
Therapeutic Effects of Benzz 180mg Injection
This medication belongs to the alkylating agent class, functioning by inducing DNA damage and interrupting the cell cycle, ultimately resulting in the death of cancer cells. It forms covalent bonds with DNA, hampers DNA repair enzymes, and impedes cell cycle advancement. As a cytotoxic drug, it effectively eliminates cancer cells by obstructing their DNA and cell cycle processes.
Interaction of Benzz 180mg Injection with other drugs
Ensure to inform your healthcare provider about all medications you are currently taking, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Some medications may interact with Benzz 180 mg Injection, potentially reducing its effectiveness and causing undesirable side effects.
More Information about Benzz 180mg Injection
- Store Benzz 180 mg Injection in the refrigerator (2°-8°C). Do not freeze.
- Keep it out of reach from children and pets.
- It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.
How to consume Benzz 180mg Injection
This medication will be administered to you by a healthcare professional within a hospital setting. The injection will be administered intravenously into a vein in your arm or hand. It is important not to self-administer this medication. The dosage of the injection will be determined by your doctor based on your specific disease condition and other relevant factors. Benzz 180 mg Injection is typically administered approximately 30 minutes before receiving anti-cancer medicine (chemotherapy) or immediately before anesthesia for surgery. Throughout the infusion, you will be closely monitored for any side effects or reactions to the medication. The infusion process usually takes several hours to complete, and you may require multiple infusions over several weeks.
Safety Advices for Benzz 180mg Injection
Pregnancy
Benzz 180 mg Injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Breast Feeding
It is not known if Benzz 180 mg Injection passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.
Liver
Inform your doctor if you have any liver problems before taking Benzz 180 mg Injection. Regular monitoring of liver function tests is recommended.
Alcohol
Consuming alcohol may affect the effectiveness of Benzz 180 mg Injection. Stop consuming alcohol if you are taking this medicine.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking Benzz 180 mg Injection, it may cause dizziness and impair your concentration.
Side Effects of Benzz 180mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Severe allergic reactions
- Bone marrow suppression
- Abnormal liver function
- Tumor lysis syndrome
Common
- Infection, fever
- Low blood cell count
- Headache, dizziness
- Nausea, vomiting
- Increased blood level of creatinine and urea (chemical waste products)
- Mucosal inflammation, sore mouth
- Insomnia, fatigue
- Hair loss, itching, rash
- Diarrhea, constipation
- Missed periods
- Dehydration, loss of appetite
- Low or high blood pressure
Word of Advice
Benzz 180 mg Injection carries risks for fetal development and nursing infants, so it’s crucial to discuss contraception options and the importance of avoiding breastfeeding during treatment. This medication may induce fatigue, so it’s advisable for patients to prioritize adequate rest and self-care during treatment. Given its propensity to increase the risk of bleeding and bruising, caution should be exercised when handling sharp objects or engaging in activities that may lead to injury.
FAQs
Q 1. What is Benzz 180 mg Injection used for?
Benzz 180 mg Injection is a chemotherapy drug used to treat various types of cancers, including non-Hodgkin’s lymphoma, chronic lymphocytic leukaemia, and multiple myeloma.
Q 2. How will I receive Benzz 180 mg Injection?
Benzz 180 mg Injection is administered into a vein as a short-term infusion over 30 – 60 minutes.
Q 3. How does Benzz 180 mg Injection work to treat cancer?
Benzz 180 mg Injection works by damaging the DNA in cancer cells, preventing them from multiplying and spreading.
Fact Box of Benzz 180mg Injection
Molecule name: Bendamustine
Pharmacological class: Alkylating agents
Therapeutic class: Antineoplastics
Indications:
1. Chronic lymphocytic leukaemia. 2. Non-Hodgkin’s lymphomas 3. Multiple myeloma
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