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Introduction to Bavencio 200mg Injection 10ml
Bavencio 200mg/10ml injection contains the active ingredient avelumab. It falls under the category of antineoplastic drugs known as PD-1/PD-L1 (programmed death ligand-1) inhibitors. This medication is utilized to treat Merkel cell carcinoma, a rare form of skin cancer that has metastasized to other areas of the body in adults and children aged 12 and above. It is also indicated for the treatment of urothelial carcinoma, a type of cancer originating in the urinary tract that has spread to nearby tissues or other parts of the body in individuals whose cancer has progressed during or within 12 months after receiving other anticancer medications.
Additionally, it is utilized in conjunction with other anticancer medications to manage renal cell carcinoma, a form of kidney cancer that has metastasized to other areas of the body. PD-L1, located on the surface of certain cancer cells, aids in shielding them from the immune system. Its mechanism involves slowing or halting the proliferation and dissemination of cancer cells. Refrain from using Bavencio 200mg/10ml injection if you are allergic to avelumab or any other components of this medication. Prior to commencing therapy, notify your physician if you have liver diseases, hepatitis B, HIV/AIDS, or other immune disorders.
This medication is not advised for use in children and adolescents under 18 years old. If you experience any reactions such as infusion-related reactions, inflammation of the lungs, liver, pancreas, watery stools, or diarrhea, promptly inform your doctor and seek medical attention. Bavencio 200mg/10ml injection is contraindicated in pregnant and breastfeeding women. Inform your physician if you are pregnant or breastfeeding. Employ effective contraception throughout the therapy to prevent pregnancy. Common adverse reactions include fatigue, muscle pain, diarrhea, nausea, rash, decreased appetite, urinary tract infection, and swelling in various parts of the body.
Uses of Bavencio 200mg Injection 10ml
- Merkel cell carcinoma
- Urothelial carcinoma
- Renal cell carcinoma
Therapeutic Effects of Bavencio 200mg Injection 10ml
Bavencio 200mg/10ml injection is a monoclonal antibody, a specialized type of protein, designed to target a specific site in the body known as PD-L1. By binding to PD-L1, it interrupts its protective function, thereby enabling the immune system to effectively combat tumor cells. Additionally, it triggers antibody-dependent cell-mediated cytotoxicity, ultimately resulting in the death of cancer cells.
Interaction of Bavencio 200mg Injection 10ml with other drugs
Notify your healthcare provider about all medications you are taking, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Some medications may interact with Bavencio 200mg/10ml injection, potentially diminishing its effectiveness and leading to undesirable side effects.
More Information about Bavencio 200mg Injection 10ml
- Store in a refrigerator (2°C to 8°C).
- Do not freeze. Store in the original package to protect from light.
- keep the injection away from the reach of children and pets.
- If you have missed any dosing appointments, inform your doctor and schedule immediately.
How to consume Bavencio 200mg Injection 10ml
A doctor or nurse trained in cancer chemotherapy will administer this medication to you in a hospital or clinic setting. It will be delivered as an intravenous infusion drip into your vein, which typically takes one hour. Do not attempt to self-administer the injection. Your doctor will determine the appropriate dosage and duration of treatment based on factors such as the severity of your disease, your body weight, and other relevant considerations.
Safety Advices for Bavencio 200mg Injection 10ml
Pregnancy
Bavencio 200mg/10ml injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 1 months after your last dose is necessary.
Breast Feeding
Breastfeeding is not recommended in patients taking Bavencio 200mg/10ml injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Liver
Bavencio 200mg/10ml injection is safe to administer in patients with liver problems. Dose adjustments are not necessary. However, inform your physician if you have any liver diseases or problems before initiating the therapy.
Alcohol
It is unknown whether consuming alcohol is safe during the treatment with Bavencio 200mg/10ml injection. Inform your doctor if you are a chronic drinker.
Driving
Bavencio 200mg/10ml injection may make you feel tired, dizzy, or sleepy. It is unsafe to drive or operate heavy machinery after taking this medicine.
Side Effects of Bavencio 200mg Injection 10ml
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Increased blood pressure
- Swelling in the legs and feet
- Skin rash
- Abdominal pain
- Decrease in appetite
- Diarrhea
- Nausea
- Decreased RBC counts
- Muscle pain
- Cough, shortness of breath
- Difficulty in talking
- Tiredness
Serious
- Heart problems
- Severe skin reactions
- Thyroid problems
- Liver injury
- Visual impairment
- Infusion reactions
Word of Advice
Notify your doctor promptly if you experience symptoms of infection, anemia, or bleeding. Refrain from breastfeeding during the treatment and for one month following the final dose. Prior to starting therapy, inform your doctor if you have kidney disease, liver disease, heart disease, diabetes, lung or respiratory issues, or gastrointestinal problems. Do not discontinue the injection without consulting your physician, as interrupting your treatment may diminish the medication’s efficacy. Your doctor may request specific tests to assess the effectiveness of the therapy and monitor any adverse effects.
FAQs
Q 1. How long should I have to take Bavencio 200mg/10ml injection?
Bavencio 200mg/10ml injection is given as a cycle therapy. Your doctor will decide the dose and duration of the therapy based on your disease severity and condition.
Q 2. Can I take vitamin supplements with Bavencio 200mg/10ml injection?
Certain medications may interact with the effectiveness of Bavencio 200mg/10ml injection including prescription, over-the-counter medicines, vitamin or nutritional supplements, and herbal products. Inform your physician about your medication history.
Q 3. Is Bavencio 200mg/10ml injection cardiotoxic?
Heart problems like cardiac arrest and congestive heart failure may occur in patients receiving this medicine for the long term. Inform your physician of any pre-existing heart disorders before initiating the treatment.
Fact Box of Bavencio 200mg Injection 10ml
Molecule name: Avelumab
Pharmacological class: PD-1, PD-L1 inhibitors
Therapeutic class: Antineoplastics
Indications:
1. Merkel cell carcinoma 2. Urothelial carcinoma 3. Renal cell carcinoma
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