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Introduction to Arganat 250mg Injection
Arganat 250mg injection, containing the active substance Argatroban, serves as an anticoagulant medication. It is specifically employed in managing heparin-induced thrombocytopenia (HIT), a rare yet severe complication arising from the use of heparin, a widely used anticoagulant. The mechanism of Arganat involves attaching to the active site of thrombin, a crucial enzyme in the clotting process. By inhibiting thrombin’s ability to trigger other factors necessary for clot formation, it effectively prevents the formation of blood clots.
Do not use Arganat 250mg injection if you have an allergy to Argatroban or any component of this medication. It is also contraindicated in individuals with uncontrolled bleeding or significant liver dysfunction. Inform your healthcare provider if you are at a heightened risk of bleeding or have recently received other anticoagulant treatments, including heparin injections or infusions. This medication is not recommended for individuals under the age of 18.
Uses of Arganat 250mg Injection
- Heparin-induced thrombocytopenia.
- Patients with a risk of heparin-induced thrombocytopenia undergoing percutaneous coronary intervention (PCI).
Therapeutic Effects of Arganat 250mg Injection
The mechanism of action of Arganat 250mg injection involves its binding to the active site of thrombin, a crucial enzyme involved in the formation of blood clots. By doing so, it inhibits thrombin from activating other clotting factors, thus preventing the formation of clots.
Interaction of Arganat 250mg Injection with other drugs
Notify your physician of any prescribed medications, over-the-counter drugs, dietary or vitamin supplements, as well as herbal products you are currently taking or have taken prior to beginning treatment. Some medications may interact with Arganat 250mg injection, potentially leading to adverse effects.
More Information about Arganat 250mg Injection
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Do not store above 30°C.
- Always check the expiry date before consuming it.
How to consume Arganat 250mg Injection
A healthcare provider will administer Arganat 250mg injection to you in a hospital setting, typically through a vein (intravenously). Your doctor will determine the appropriate dose, route of administration, and frequency based on your medical condition and other relevant factors.
Safety Advices for Arganat 250mg Injection
Pregnancy
It is unknown whether Arganat 250mg injection is harmful to the unborn baby. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant.
Breast Feeding
Taking Arganat 250mg injection while breastfeeding may be unsafe because it may affect the child. Inform your doctor if you are breastfeeding.
Liver
Arganat 250mg injection should be used cautiously in patients with liver conditions. Before starting the treatment, inform your physician about pre-existing liver conditions. Your doctor will adjust the dose if needed.
Alcohol
It is unsafe to consume alcohol while taking Arganat 250mg injection. Please speak with your physician.
Driving
Do not drive a car or operate machinery while undergoing treatment with Arganat 250mg injection, as it contains alcohol.
Side Effects of Arganat 250mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Bleeding or bruising
- Blood in urine or stools
- Vomiting or coughing up blood
- Black stools
- Difficulty in breathing
- Cold sweaty skin
- Dry mouth
- Dilated pupils and/or weak rapid pulse
Common
- Anaemia
- Blood clotting
- Purpura bleeding (numerous small bleeding in the skin and mucus membranes)
- Nausea
Word of Advice
Patients with liver conditions should approach the use of Arganat 250mg injection with caution and disclose all underlying medical conditions to their physician. Refrain from discontinuing the medication without medical guidance. Avoid doubling the dosage to compensate for a missed dose. Individuals with HIT type II face an elevated risk of developing potentially life-threatening blood clots, which can result in heart attacks, strokes, respiratory issues, and impaired blood circulation in the limbs. This medication can aid in preventing or mitigating these complications.
FAQs
Q 1. How to manage the side effects of Arganat 250mg injection?
To manage the side effects of Arganat 250mg injection, follow the prescribed dosage, and report side effects promptly. Stay hydrated, and monitor blood pressure regularly. Maintain a healthy lifestyle, and attend follow-up appointments.
Q 2. When to stop Arganat 250mg injection before surgery?
The decision to discontinue Arganat 250mg injection before surgery should be made by a healthcare professional, taking into consideration various factors such as the type of surgery, the patient’s underlying medical condition, and the risk of bleeding. So, consult your doctor for more information.
Q 3. Can you take Arganat 250mg injection when pregnant?
Consult your medical professional regarding the use of Arganat 250mg injection during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it’s necessary.
Fact Box of Arganat 250mg Injection
Molecule Name: Arganat 250mg injection
Pharmacological class: Thrombin Inhibitors
Therapeutic class: Anticoagulants
Indications:
1. Heparin-induced thrombocytopenia
2. Patients with a risk of heparin-induced thrombocytopenia undergoing percutaneous coronary intervention (PCI)
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