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Colistimethate Sodium

This page contains brief details about the drug colistimethate sodium, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Colistimethate Sodium is a polymixin antibiotic agent. Initially, Colistin was discovered in 1947, and FDA approved Colistimethate sodium was approved for medical use in 1970

Mechanism of Action of Colistimethate Sodium

Colistimethate sodium, a polypeptide antibiotic, penetrates and disrupts the bacterial cell membrane of susceptible strains of aerobic gram-negative bacteria. It works by killing bacteria

AVAILABLE BRANDS

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Kallistro 4.5MIU Injection
BHARAT SERUMS & VACCINES LTD ₹1697.00
Kallistro 1MIU Injection
BHARAT SERUMS & VACCINES LTD ₹339.00
Kallistro 2MIU Injection
BHARAT SERUMS & VACCINES LTD ₹566.00
Guficol 3MIU Injection
GUFIC BIOSCIENCE LTD ₹735.00

Uses of Colistimethate Sodium

Colistimethate Sodium is used to treat certain types of infections caused by bacteria. This medicine is commonly used when other antibiotics are not suitable. It is sometimes given as an inhalation to treat chronic chest infections in patients with cystic fibrosis. This medicine is used when these infections are caused by specific bacteria called Pseudomonas aeruginosa.

Colistimethate Sodium Drug administaration and Dosage available

A doctor or nurse in a hospital or clinic setting will give it to you. Depending on the reason, the drug may be given by fast or slow injection into a vein. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.

Warnings, Precautions and Side Effects of Colistimethate Sodium

Warnings

Do not use this medicine if you are allergic to colistimethate sodium, colistin, or to other polymers in the medication. Inform your doctor if you are pregnant or breastfeeding during the treatment. Serious allergic reactions can happen even with the first dose of colistimethate sodium. They can include rapid development of rashes, swelling of the face, tongue, and neck, and inability to breathe. If you experience signs of an allergic reaction, you should seek urgent medical attention.

Precautions

Inform your doctor if you have kidney problems or suffer from myasthenia gravis, porphyria, and asthma. Tell your doctor if you are pregnant, breastfeeding, or planning to get pregnant during the treatment. Do not stop your treatment early without consulting a doctor. Your doctor will decide how long your treatment should last. Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Colistimethate Sodium and reduce its effectiveness by causing undesirable side effects.

Side Effects

Common side effects of Colistimethate sodium are numbness or tingling, dizziness or loss of balance, changes in blood pressure, slurred speech, vision problems, confusion and mental problems. Other serious side effects of colistimethate sodium are breathing difficulty, respiratory tract paralysis, diarrhea, and kidney damage

Word Of Advice

Do not store above 25°C). Store in the original package to protect from light. keep the injection away from the reach of children and pets. This medicine may cause kidney damage; your doctor will perform routine kidney function test. This medicine may make you feel dizzy or cause numbness and tingling in your hands and feet. Do not drive or operate heavy machines while taking this medicine. Tell your doctor immediately if you have severe, continuous, or bloody diarrhea. Sometimes injection site reactions, including itching, burning, swelling, or a lump under your skin, may occur where the needle is placed.

Frequently Asked Question

Colistimethate Sodium is available in various forms, including intravenous (IV) injection, inhalation, and oral capsules. Your physician will decide the route of administration based on the type and severity of the infection and other factors
Common side effects of Colistimethate Sodium may include dizziness, numbness or tingling sensation, especially in the face, nausea, vomiting, diarrhea, and kidney function changes. It is important to report any unusual or severe side effects to your healthcare provider.
Colistimethate Sodium treatment requires careful monitoring of kidney function because this medicine can cause kidney damage. Your healthcare provider may perform regular kidney function tests to ensure the medication is used safely and effectively.
Colistimethate Sodium can be used in pediatric patients, but the dosage and administration may vary depending on the child’s age, weight, and specific medical condition. It is important to follow the healthcare provider’s instructions and closely monitor the child’s response to treatment.

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.