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Cinacalcet
This page contains brief details about the drug abciximab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Cinacalcet is a calcimimetic drug developed by the U.S. Food And Drug Administration and initially approved for treating hyperparathyroidism.
Mechanism of Action of Cinacalcet
Cinacalcet works by increasing the sensitivity of the parathyroid gland to calcium, which reduces the release of parathyroid hormone. This helps to regulate calcium and phosphorus levels in the body.
Uses of Cinacalcet
Cinacalcet is used to treat hyperparathyroidism (overactivity of the parathyroid glands, which are small glands located in the neck) in patients with chronic kidney disease who are on dialysis. It is also used to treat hypercalcemia in patients with parathyroid carcinoma (a rare type of cancer that develops in the parathyroid glands). It helps regulate the levels of parathyroid hormone (PTH) in the body.
Cinacalcet Drug administaration and Dosage available
Take the Cinacalcet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Warnings, Precautions and Side Effects of Cinacalcet
Warnings
Before consuming this drug, inform your physician if you have had liver or heart failure or heart rhythm problems and have a history of seizures (fits or convulsions), as the risk of having seizures might be higher if you’ve experienced them. Cinacalcet should not be taken by children under the age of 18 who have parathyroid cancer or primary hyperparathyroidism. This medication is not suitable for this age group for these conditions. If you are receiving treatment for secondary hyperparathyroidism, your doctor will carefully monitor your calcium levels before you start using the drug and throughout your treatment with the medication.
Precautions
Cinacalcet helps to reduce calcium levels in the body. However, in some cases, low calcium levels (hypocalcemia) have been reported in adults and children undergoing treatment. Therefore, you must inform your physician if you develop any indicative signs of low calcium levels, such as muscle spasms, twitches, cramps, numbness or tingling sensations in your extremities or around your mouth, and loss of consciousness while receiving this drug. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. It is unknown if this medicine passes into the breast milk. Please consult your doctor before breastfeeding.
Side Effects
The side effects known to occur commonly during the treatment with Cinacalcet are dizziness, loss of appetite, muscle pain, weakness, rash, low testosterone levels, high potassium levels in the blood, upper respiratory infection, headache, low bp, cough, indigestion, diarrhea, stomach and back pain, and constipation. Some serious side effects include numbness and tingling around the mouth, muscle cramps, seizures, swelling of the face, lips, mouth, tongue, or throat, difficulty swallowing or breathing, and allergic reactions.
Word Of Advice
Cinacalcet can cause stomach upset. To minimize this, your doctor may advise you to take the medication with food or antacids. Follow your doctor’s recommendations on when and how to take the medication. Maintain proper hydration by drinking enough water throughout the day. Staying hydrated can help support your overall health and the effectiveness of your medications.
Frequently Asked Question
Cinacalcet may not be suitable for individuals with a history of hypocalcemia or hypersensitivity to the drug. It’s important to consult a healthcare provider before starting the medication.
Cinacalcet helps manage hyperparathyroidism by regulating parathyroid hormone (PTH) levels, but it may not necessarily cure the condition. It aims to improve abnormal hormone levels and associated complications.
The common side effects may include nausea, vomiting, diarrhea, loss of appetite, headache, and dizziness. More serious side effects such as low calcium levels (hypocalcemia) can also occur.
Cinacalcet is usually taken orally in the form of tablets. The dosage and frequency will be determined by your physician based on your kidney function and response to treatment.
Disclaimer
The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.