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Celecoxib

This page contains brief details about the drug celecoxib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The U.S. FDA approved Celecoxib on 31 December 1998. Celecoxib belongs to the family known as non-steroidal anti-inflammatory drugs (NSAID), and specifically a sub-group known as cyclooxygenase-2 (COX-2) inhibitors.

Mechanism of Action of Celecoxib

Celecoxib works by inhibiting COX-2 enzymes that trigger inflammation and pain, effectively reducing these symptoms in conditions like arthritis. Its selective action minimizes the risk of stomach-related issues compared to traditional NSAIDs.

Uses of Celecoxib

Celecoxib treats is used in adults for the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. In conditions like rheumatoid arthritis and osteoarthritis, excess production of prostaglandins by your body can lead to pain and inflammation. Celecoxib works by decreasing the production of prostaglandins, effectively reducing pain and inflammation.

Celecoxib Drug administaration and Dosage available

Consume the capsule at any time of the day, with or without food. If you have difficulty swallowing, sprinkle the capsule contents into a spoonful of semisolid food and swallow immediately with a glass of water.

Warnings, Precautions and Side Effects of Celecoxib

Warnings

Do not take Celecoxib if you are allergic to Celecoxib or any of its ingredients. Inform your doctor if you had reactions to sulfonamide medicines, suffer from ulcers or bleeding in the stomach or intestines, or experienced adverse reactions to NSAID medications like aspirin. Before starting the treatment, inform your doctor because it is recommended to not take this medicine if you are pregnant or are breastfeeding. Do not take this medicine if you have severe liver or kidney disease, have inflammatory intestinal conditions, or have heart-related issues such as heart failure, heart disease, or circulation problems. Additionally, if you have had surgeries on leg arteries or have a history of blood circulation problems, this medicine usage should be avoided. Celecoxib contains lactose. If you are sugar intolerant, consult your doctor before using this product. This medicine is for adults only, it is not for use in children.

Precautions

Inform your doctor about if you have a history of stomach or intestinal ulcers or bleeding (avoid if currently present), are on acetylsalicylic acid or antiplatelet therapies, use blood clotting or corticosteroid medications, or simultaneously use other non-acetylsalicylic NSAIDs like ibuprofen. Report your doctor if you have conditions such as smoking, diabetes, high blood pressure, high cholesterol, compromised heart, liver, or kidney function, fluid retention, dehydration, past severe allergic reactions to medications, ongoing infections, or are over 65 years old. Monitoring may be necessary. Notably, Celecoxib could mask fever or infection signs. Remember, alcohol combined with NSAIDs may increase gastrointestinal risks.

Side Effects

The most common side effects of Celecoxib arHigh blood pressure, urinary infections, breathlessness, flu-like symptoms, nausea, vomiting, diarrhea, indigestion, dizziness, sleeplessness, difficulty swallowing, headache, and muscle stiffness with painful joints. Serious side effects while taking Celecoxib are severe allergic reactions, severe stomach pain with black stools and blood vomiting, liver failure, heart problems including the risk of a heart attack, kidney stones, kidney toxicity, and worsened asthma symptoms

Word Of Advice

Follow the prescribed dosage and usage instructions provided by your healthcare professional. Inform your doctor about any known allergies or medical conditions you have before receiving Celecoxib. Before stating the treatment, inform your doctor if you have a kidney or liver condition, as this medicine is recommended for such conditions. If you notice any unexpected or severe side effects, like an allergic reaction, seek immediate medical attention. Inform your healthcare professional about any other medications or supplements you are consuming to avoid potential drug interactions. If you have any concerns regarding the treatment, consult your healthcare professional for information.

Frequently Asked Question

If you observe any side effects while taking Celecoxib, stay hydrated by drinking plenty of fluids. Your medical professional may also recommend over-the-counter or prescription medications to help manage your symptoms. You should contact your physician if your side effects are severe or persistent.
There are no specific dietary restrictions associated with these medications. However, it is recommended to maintain a healthy and balanced diet to support overall health and well-being.
It is unsafe to consume Ceftriaxone during pregnancy and breastfeeding. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant. Your doctor will decide whether you should use this medicine.
The time it takes for the Celecoxib to start working varies from person to person. However, it is important to continue taking the medication as your healthcare provider prescribes to achieve optimal treatment outcomes.

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.