Home > CAPMATINIB
Capecitabine
This page contains brief details about the drug capmatinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Capmatinib is an anticancer drug that belongs to the class of medications called protein kinase inhibitors. FDA approved it initially in August 2020 for treating a certain type of lung cancer.
Mechanism of Action of Capmatinib
Capmatinib is a kinase inhibitor that targets mesenchymal-epithelial transition (MET). It works by blocking the action of this abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.
Uses of Capmatinib
Capmatinib is available as a tablet. It is used to treat adults with a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other body parts or is caused by a change (mutation) in a gene that makes an enzyme called MET in adults.
Capmatinib Drug administaration and Dosage available
It is an orally available prescription drug. Your doctor will decide the dose and duration of capmatinib based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.
Warnings, Precautions and Side Effects of Capmatinib
Warnings
This drug is indicated to cause severe lung infection. Report to your physician if you have any lung problems other than lung cancer before initiating the treatment. This medicine may cause liver injury. Capmatinib should not be given to pregnant and breastfeeding women.
Precautions
Inform your physician if you have any symptoms of an allergic reaction, including rash, hives, fever, difficulty breathing, or low blood pressure. This medicine is not recommended for children and adolescents below 18. Do not take this medicine if you are allergic to capmatinib or any ingredients. Inform the physician if you have or have ever had lung or breathing problems other than your lung cancer, liver problems, or pancreatic problems. Inform your healthcare provider about all your medicines, including prescription, over-the-counter, vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications interact with capmatinib and reduce its effectiveness by causing undesirable side effects.
Side Effects
The common side effects of capmatinib are swelling in the face, and body, decrease in appetite, nausea, cough, and fatigue. Other side effects of capmatinib are vomiting, liver injury, muscle pain, shortness of breath, lung infection, and respiratory disease.
Word Of Advice
Store at 20°C to 25°C. Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets. If you forgot to take the tablet, take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose. Limit direct exposure to the sun or artificial ultraviolet (UV) light while using this medicine. Use sunscreen, wear sunglasses and protective clothing while you are going outdoors, and for at least 7 days after you stop taking it.
Frequently Asked Question
Inform your physician about all your medical and medication history, including over-the-counter medicines and nutritional or vitamin supplements you are taking.
The duration of your treatment depends on your disease condition and severity. Your doctor will decide your dose, and duration of your treatment.
Yes, capmatinib is safe when prescribed to patients with kidney diseases. No dose adjustments are necessary. Inform your physician if you have any kidney diseases before initiating the treatment.
Yes, capmatinib is a targeted therapy. They work by targeting a mutation in MET gene. This helps slow or stop the spread of cancer cells.
Disclaimer
The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.