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Basiliximab

This page contains brief details about the drug basiliximab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The U.S. FDA-approved Basiliximab to prevent the rejection of kidney transplants on May 12, 1998. Basiliximab injection is an immunosuppressant with an active ingredient called Basiliximab. It belongs to the medication class known as monoclonal antibody.

Mechanism of Action of Basiliximab

Basiliximab is a monoclonal antibody. It targets and inhibits the activation of an interleukin-2 receptor alpha (IL-2Rα) receptor. This action will reduce the activation and proliferation of immune cells, particularly T lymphocytes (T cells), which are involved in organ rejection.

AVAILABLE BRANDS

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Simulect 20mg Injection
NOVARTIS INDIA LTD ₹77,000.00

Uses of Basiliximab

Basiliximab is employed to prevent kidney transplant rejection and is administered via injection during the initial 4 to 6 weeks post-transplant. Its use extends to adults, adolescents, and children alike.

Basiliximab Drug administaration and Dosage available

A healthcare professional will administer the medication to you in a hospital environment. Typically, it is given as an intravenous injection directly into a vein. Your doctor will determine the appropriate dosage, method of administration, and frequency according to your specific disease condition and individual factors.

Warnings, Precautions and Side Effects of Basiliximab

Warnings

Avoid taking this medication if you are pregnant, breastfeeding, or allergic to Basiliximab or any of its components. Before initiating treatment, inform your doctor if you’ve previously undergone a transplant that failed shortly afterward or if you’ve had an unsuccessful transplant surgery. Additionally, if you are over 65 years old, as this medication has not been studied in this age group, it’s important to inform your medical professional. For further information, reach out to your doctor.

Precautions

Prior to receiving any vaccine, it is imperative to consult your doctor. Notify your physician if you are pregnant or intending to conceive. Employ reliable contraception methods to prevent pregnancy during treatment and for up to 4 months following the final dose. Avoid breastfeeding for up to four months after the second dose. Address any fertility concerns with your doctor and discuss suitable contraceptive measures, as this medication should not be used during pregnancy.

Side Effects

Typical side effects of Basiliximab may include constipation, nausea, diarrhea, sudden weight gain, increased hair growth, infections, high blood pressure, and a runny nose. Serious side effects while using Basiliximab may manifest as severe allergic reactions, characterized by swelling of the face, tongue, or lips, difficulty breathing, rapid heartbeat, dizziness, and decreased urine output.

Word Of Advice

Keep Basiliximab stored in a cool, dry place, shielded from direct heat and light. Specifically, store it in the refrigerator at temperatures between 2°C to 8°C. Avoid refrigerating or freezing the medication. For further inquiries or concerns, consult your doctor. In case you miss any scheduled doses, promptly inform your doctor and reschedule accordingly.

Frequently Asked Question

If you experience diarrhea while taking Basiliximab, stay hydrated by drinking plenty of fluids. Your medical professional may also recommend over-the-counter or prescription medications to help manage your diarrhea. If your diarrhea is severe or persistent, you should contact your doctor.
Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking Basiliximab if your doctor advises you to stop.
A well-trained physician or nurse should always inject intravenous injection into the patient. Kindly do not self-administer the Basiliximab injection.
Notify your medical professional if you experience any side effects, especially allergic reactions with swelling of the face, tongue, or lips, difficulty in breathing, fast heartbeat, dizziness, or decreased urine output.

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.