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AVANAFIL

This page contains brief details about the drug avanafil, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Avanafil is a class of impotence agents that belongs to the category of medicines known as phosphodiesterase type 5 (PDE5) inhibitors. It was approved by the U.S. Food and Drug Administration on April 27, 2012 for treating erectile dysfunction.

Mechanism of Action of Avanafil

Avanafil functions by inhibiting the enzyme PDE5, which typically breaks down cyclic guanosine monophosphate (cGMP). By obstructing PDE5, Avanafil raises cGMP levels, facilitating the relaxation of smooth muscles in the penile area and enhancing blood circulation, ultimately resulting in an erection.

AVAILABLE BRANDS

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Avanair 100mg Tablet
CIPLA LTD ₹206.00
Avanair 200mg Tablet
CIPLA LTD ₹320.00

Uses of Avanafil

Avanafil has been formulated to address erectile dysfunction (ED), commonly referred to as impotence, a condition characterized by the inability to sustain an erection adequate for satisfactory sexual activity.

Avanafil Drug administaration and Dosage available

This medication is available as an oral prescription. Your doctor will determine the appropriate duration and dosage based on your medical condition and other relevant factors. Take one Avanafil Tablet approximately 30 minutes before engaging in sexual activity. Refrain from opening, breaking, chewing, or crushing the tablet; instead, swallow it whole with water.

Warnings, Precautions and Side Effects of Avanafil

Warnings

Do not use this medication if you have a known allergy to the drug or any of its components. Avanafil is intended solely for adult men, and it should not be used by children or women. Similar to other PDE5 inhibitors, Avanafil has been linked to priapism, a condition characterized by prolonged erection. If you experience an erection lasting longer than four hours, seek immediate medical attention. Untreated priapism can lead to penile damage and permanent erectile dysfunction. Before taking this tablet, inform your physician if you have any significant bleeding disorders or are currently undergoing treatment for an ulcer. This medication may increase the risk of bleeding disorders and peptic ulcers (in the stomach or duodenum).

Precautions

This medication may lead to a sudden drop in blood pressure. Notify your doctor if you have a history of heart conditions, low blood pressure, chest pain, or other cardiovascular issues. In rare instances, sudden vision or hearing loss has been associated with Avanafil use. If you encounter sudden changes in vision or hearing, cease taking the medication immediately. Drinking grapefruit juice or alcohol while using this tablet may heighten the risk of adverse effects. It’s recommended to restrict or abstain from consuming alcohol and grapefruit juice while using this medication.

Side Effects

Common side effects that may occur during Avanafil treatment include flushing (a sensation of warmth in the ears, neck, and face), headache, back pain, nasopharyngitis (inflammation of the nasal passages), and nasal congestion (stuffy nose). However, serious side effects may also include priapism, loss of vision, loss of hearing, and blurred vision.

Word Of Advice

Avanafil does not induce spontaneous erections by itself. Sexual stimulation is necessary for achieving an erection. Engage in customary sexual foreplay and stimulation as desired. This medication is taken on an as-needed basis before sexual activity and is not meant for daily use. It’s crucial not to exceed the recommended dosage frequency or take more than one dose within a day, as doing so may elevate the risk of experiencing serious side effects.

Frequently Asked Question

No, Avanafil is not approved for use in women. It is specifically used to treat male sexual problems (erectile dysfunction).
Avanafil can have side effects. Common side effects may include headache, flushing, nasal congestion, back pain, and dizziness. If you experience any severe side effects, it’s important to consult your healthcare provider.
Avoid smoking cigarettes and alcohol consumption while on treatment with Avanafil as it increases your risk of side effects.
The recommended starting dose of Avanafil is usually 50 or 100 milligrams (mg), taken as needed. However, your doctor may adjust the dosage based on your response and tolerability. The maximum dose is 200 mg daily, and it is necessary not to exceed this limit.
Avanafil starts working within 30 minutes of its administration, and the effect usually lasts 2 to 4 hours.

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.