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ANIDULAFUNGIN

This page contains brief details about the drug anidulafungin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Anidulafungin is an antifungal medication developed by the U.S. Food And Drug Administration and initially approved on 21 Feb 2006 for treating serious fungal infections.

Mechanism of Action of Anidulafungin

The mechanism of action of Anidulafungin involves the inhibition of beta-glucan synthesis in the cell walls of susceptible fungi. This interference weakens the fungal cell wall, ultimately resulting in the demise of the fungus.

AVAILABLE BRANDS

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Anidafung 100mg Injection Injection
GUFIC BIOSCIENCE LTD ₹6,999.00
Anidulan 100mg Injection Injection
MYLAN PHARMACEUTICALS PRIVATE ₹5,950.00
Eraxis 100mg Injection
PFIZER LTD ₹10,518.20

Uses of Anidulafungin

Anidulafungin is utilized in the treatment of specific invasive fungal infections, demonstrating effectiveness against various forms of invasive candidiasis, including candidemia (Candida bloodstream infection) and esophageal candidiasis (fungal infection affecting the esophagus). Invasive candidiasis arises when candida yeasts infiltrate the bloodstream or other internal organs, leading to systemic infections.

Anidulafungin Drug administaration and Dosage available

The administration of Anidulafungin involves direct intravenous (IV) delivery. It comes in the form of a powder for reconstitution, and a healthcare provider will prepare and administer the medication through a vein. Typically, the IV infusion is administered over a duration of one to two hours.

Warnings, Precautions and Side Effects of Anidulafungin

Warnings

This medication is not recommended for individuals with a known hypersensitivity or allergy to it or its components. If you encounter liver issues during the course of your treatment, your doctor may opt for more frequent monitoring of your liver function. Anidulafungin undergoes primary metabolism in the liver, underscoring the importance of regular assessment of liver function, particularly in patients with pre-existing liver conditions. It is crucial to inform your healthcare provider, including anesthesiologists, about your use of this medication, especially before undergoing surgery or receiving anesthesia. Given potential interactions between specific anesthetics and this medication, it is imperative for medical professionals to have knowledge of your medication history.

Precautions

Be attentive to any unusual symptoms such as shortness of breath, breathing difficulties, lightheadedness, or dizziness while undergoing treatment with this medication. In the event of experiencing any of these symptoms, promptly contact your physician. The safety of Anidulafungin for pregnant women is uncertain, and its use is not recommended during pregnancy due to limited data. If a woman of childbearing age is prescribed this medication, it is crucial to use effective contraception throughout the treatment period to prevent pregnancy. The impact of this medication on breastfeeding women is not well-understood, and breastfeeding women should consult their doctor for advice before taking this medicine.

Side Effects

Commonly observed side effects during Anidulafungin treatment include low blood potassium (hypokalemia), diarrhea, nausea, headache, and vomiting. Additionally, more serious side effects may include convulsions (seizures), flushing, rash, pruritus (itching), hot flush, hives, wheezing, coughing, and difficulty breathing.

Word Of Advice

Anidulafungin is administered via intravenous infusion. Certain individuals might encounter infusion-related reactions, such as a rash, hives, itching, or redness at the infusion site. If you observe any of these symptoms during or after the infusion, promptly inform your physician.

Frequently Asked Question

Anidulafungin is administered intravenously (IV). The medication comes in the form of a powder that needs to be reconstituted before administration. The physician will prepare and administer the IV infusion through a vein. The infusion typically takes one to two hours.
Common side effects of Anidulafungin may include fever, diarrhea, nausea, vomiting, headache, and mild changes in liver function tests. You should contact your physician immediately if you experience any severe side effects.
The dosing frequency of Anidulafungin may vary based on the severity of the infection and the individual’s response to treatment. It is usually given once daily.
Anidulafungin is approved for use in pediatric patients aged one month and older to treat invasive candidiasis. The dosing in children is based on their weight and medical condition.
People with known allergies to echinocandins should avoid this medication. Also, individuals with severe liver problems or a history of hypersensitivity to Anidulafungin should not take it. 

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.