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Acyclovir

This page provides concise information about the drug acyclovir, including its indications, dosage and administration, mechanism of action, related brands with strengths, warnings, and common side effects.

Background and Date of Approval

Acyclovir received approval from the U.S. FDA for the treatment of individuals with herpes simplex virus infections, chickenpox, and shingles on December 30, 2002.

Mechanism of Action of Acyclovir

The injection of Acyclovir hinders the activity of the herpes virus enzyme known as DNA polymerase and disrupts DNA synthesis, thereby halting the process of viral replication.

Uses of Acyclovir

Acyclovir injection is an antiviral medication employed for the treatment of chickenpox (a contagious infection with an itchy rash and fluid-filled blisters), shingles (a blistering, painful rash affecting one side of the body), and herpes infections (including cold sores and genital herpes). Moreover, it is utilized to prevent the recurrence of these conditions and to safeguard individuals with compromised immune systems from infections.

Acyclovir Drug administaration and Dosage available

Acyclovir is administered through intravenous infusion into the vein. If prescribed for you, a healthcare professional will administer the injection; do not attempt self-administration. Your physician will determine the dosage and administration frequency based on your medical condition, as it varies for each individual.

Warnings, Precautions and Side Effects of Acyclovir

Warnings

Avoid taking this medication if you are allergic to Acyclovir, Valaciclovir, or any of its other components. Prior to commencing the treatment, disclose to your doctor any existing kidney conditions. Consult your physician if you follow a low-sodium diet or are experiencing dehydration (excessive thirst). Inform your doctor if you are either 65 years of age or younger, or if you are a child.

Precautions

Inform your physician if you believe you are pregnant, planning to conceive, or currently breastfeeding. Additionally, notify your doctor if you are taking any other medications alongside Axovir 250mg injection. Driving while undergoing Axovir 250mg treatment may lead to tiredness and drowsiness, affecting your ability to concentrate. For further details, consult your doctor. Dosage adjustments may be considered for pediatric patients and those with kidney conditions.

Side Effects

Nausea, vomiting, rash, itching, sensitivity to light, redness, and swelling at the injection site are the prevalent side effects associated with Acyclovir.
Severe allergic reactions, breathing difficulties, and facial swelling are notable serious side effects that may occur during Acyclovir treatment.

Word Of Advice

Notify your doctor of any medications you are taking. Adhere to the prescribed dosage and complete the entire treatment, even if symptoms improve before the designated period ends. Practice safe sex. Reach out to your physician for any questions, doubts, or concerns about the medication. Ensure Axovir 250mg Injection is kept out of sight and reach of children, and store it below 25°C.

Frequently Asked Question

It is unknown whether the Acyclovir injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Yes, contact your doctor if you experience any side effects. Additionally, during the treatment with Acyclovir, it is mandatory to keep yourself hydrated; hence drink plenty of water.
One of the common side effects of Acyclovir injection is skin rash and itching. This usually gets normal when your treatment finishes. Contact your doctor if you experience it.
Acyclovir injection is prescribed for both adults and children. But before consuming, consult your doctor and mention your children’s age to find the right dosage.
Storage condition of Acyclovir injection is not stored above 25°C.

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Antiviral agents (Nonretroviral), 12th edition, 2011, 1594.
  2. KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 799.
  3. Wockhardt UK Limited, Electronic medicines compendium (emc), [ Revised on Feb 2018] [ Accessed on 15th May 2023],https://www.medicines.org.uk/emc/files/pil.6175.pdf
  4. GlaxoSmithKline, US Food and Drug Administration, [ Revised on Nov 2003] [ Accessed on 15th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/18603slr027_zovirax_lbl.pdf

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.