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Cefuroxime

This page contains brief details about the drug cefuroxime, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Cefuroxime contains an active component as cefuroxime. It is an antibiotic medication used to treat a variety of bacterial infections. It belongs to the class of antibiotics known as cephalosporins. This medication has a broad spectrum of activity against gram-positive and gram-negative bacteria. Cefuroxime received its initial approval from the U.S. Food and Drug Administration (FDA) on June 13, 1984. This approval was for the intravenous (IV) formulation of cefuroxime, which treats various bacterial infections.

Mechanism of Action of Cefuroxime

The therapeutic effect of cefuroxime is the inhibition of bacterial growth and the treatment of various bacterial infections. By targeting and interfering with the synthesis of bacterial cell walls, this medication effectively inhibits the growth and spread of susceptible bacteria. It exhibits a broad spectrum of activity against gram-positive and gram-negative pathogens commonly involved in respiratory tract infections, urinary tract infections, skin and soft tissue infections, and certain sexually transmitted infections.

AVAILABLE BRANDS

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Cefoprit 1.5gm Injection
UNITED BIOTECH PVT LTD ₹223.00
Cefutic 500mg Tablet
CURETIC BIOTECHS PVT LTD ₹449.00
Cefoprim 500mg Tablet
UNITED BIOTECH PVT LTD ₹374.00
Bipacef 500mg Tablet
MICRO LABS LTD ₹336.00
Cefoprit 500mg Tablet
UNITED BIOTECH PVT LTD ₹190.00
Ct-Rax 250mg Tablet
SERVO LIFE SCIENCES ₹250.00

Uses of Cefuroxime

This medication has a broad spectrum of activity against gram-positive and gram-negative bacteria. This medication is commonly used to treat respiratory tract infections, such as bronchitis and pneumonia, urinary tract infections, skin and soft tissue infections, and certain sexually transmitted infections like gonorrhea.

Cefuroxime Drug administaration and Dosage available

To use cefuroxime, follow the instructions provided by your healthcare provider or as indicated on the medication label. It is available in various forms, including extended-release tablets and intravenous (IV) injections. If taking the oral tablets, swallow them whole with a full glass of water, with or without food, as directed. If using extended-release tablets, do not crush or chew them. For intravenous administration, it is typically administered by a healthcare professional in a clinical setting. The dosage and duration of treatment will depend on the type and severity of the infection.

Warnings, Precautions and Side Effects of Cefuroxime

Warnings

Cefuroxime carries certain warnings that should be considered when using the medication. These include the possibility of severe allergic reactions, such as anaphylaxis, which requires immediate medical attention. There is also a risk of developing Clostridium difficile-associated diarrhea, a potentially serious condition characterized by persistent diarrhea. This medication may cause skin reactions ranging from mild rashes to severe conditions like Stevens-Johnson syndrome or toxic epidermal necrolysis. This medication can occasionally lead to liver dysfunction, as indicated by elevated liver enzymes. Although rare, central nervous system effects have been reported, such as confusion or seizures. Lastly, prolonged or repeated use of this medicine can result in the overgrowth of non-susceptible organisms, including fungi, leading to secondary infections.

Precautions

When using Cefuroxime, it is important to be aware of potential warnings. It is important to be aware of these potential skin reactions and seek medical help if any skin changes occur and monitor for these symptoms, and contact a healthcare provider if they arise. Vigilance and prompt reporting of new or worsening symptoms are essential to ensure cefuroxime’s safe and effective use. Contact your healthcare provider if you experience severe or persistent diarrhea during or after treatment. Avoid alcohol consumption while taking cefuroxime, as it can interact with the medication and potentially increase the risk of side effects. Adhering to these precautions and following your healthcare provider’s guidance can help ensure the safe and effective use of cefuroxime.

Side Effects

Cefuroxime, like any medication, can cause side effects. Common side effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal pain. Headaches, dizziness, and skin rash are also reported. These side effects are generally mild and resolve on their own. However, more serious side effects can occur, albeit rarely, including severe allergic reactions, liver dysfunction, and blood disorders.

Word Of Advice

Inform your healthcare provider about any known allergies or sensitivities to cephalosporin antibiotics and any other medications or substances you are currently taking. Additionally, disclose your medical history, especially if you have a history of kidney disease, liver disease, gastrointestinal disorders, or blood clotting disorders. Use cefuroxime with caution if you have a history of severe allergic reactions or asthma. Pregnant and breastfeeding women should consult a doctor before taking it. It is crucial to complete the full course of treatment as prescribed and not to skip any doses, even if symptoms improve, to ensure the infection is fully treated. If you develop severe or persistent diarrhea during or after treatment, contact your healthcare provider, as it could be a sign of a serious intestinal infection. It is advisable to consult a healthcare professional to determine the appropriate dosage for both geriatric and pediatric populations.

Frequently Asked Question

It is important to complete the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve. Stopping the medication prematurely can lead to incomplete eradication of the bacteria and may increase the risk of antibiotic resistance.
Cefuroxime is a cephalosporin antibiotic, and cross-reactivity between cephalosporins and penicillins may occur in individuals with a penicillin allergy. It is crucial to inform your healthcare provider about any known allergies, including penicillin, to determine the appropriate course of action.
While sun sensitivity is not a commonly reported side effect of cefuroxime, it is always a good practice to take precautions and protect your skin from excessive sun exposure. Use sunscreen, wear protective clothing, and limit sun exposure during peak hours.
Cefuroxime can interfere with certain laboratory tests, such as the Coombs test, which detects certain types of antibodies. Inform your healthcare provider and laboratory personnel about your use to ensure accurate test results.

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.