Home > CARFILZOMIB

Carfilzomib

This page contains brief details about the drug carfilzomib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Carfilzomib was approved by the FDA on July 20, 2012, as a treatment for patients with multiple myeloma who have not responded to at least two prior therapies or whose disease has progressed within 60 days of completion of the last therapy. It is often used in combination with other medications.

Mechanism of Action of Carfilzomib

Carfilzomib is a proteasome inhibitor, which means it works by blocking the action of proteasomes, the enzymes responsible for breaking down proteins in cells. By blocking proteasomes, this medication can prevent the growth and survival of cancer cells, ultimately leading to the death of cancer cells. This can slow or stop the progression of multiple myeloma and may improve survival rates for some patients.

AVAILABLE BRANDS

VIEW ALL
Kyprolis 60mg Injection
DR REDDY'S LABORATORIES LTD ₹39999.00
Carzomib 60mg Injection
HETERO HEALTHCARE LTD ₹7250.00
Carfizome 60mg Injection
INTAS PHARMACEUTICALS LTD ₹8791.00
Kyfil 60mg Injection
MSN LABORATORIES (INDIA) ₹10742.00

Uses of Carfilzomib

Carfilzomib is a medication used in the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow.

Carfilzomib Drug administaration and Dosage available

Carfilzomib is typically administered as an intravenous (IV) injection by a healthcare provider. The exact dosing and frequency of administration will depend on the specific condition being treated and other individual factors, such as the patient’s age, weight, and overall health. If a dose is missed, it’s important to contact your healthcare provider as soon as possible. Suppose the missed dose is discovered within a few hours of the scheduled time. In that case, your healthcare provider may recommend administering the missed dose as soon as possible while maintaining the usual interval between doses. However, if more than a few hours have passed since the missed dose, your healthcare provider may recommend skipping the missed dose and resuming the regular dosing schedule at the next scheduled time. Avoid double-up on doses to make up for a missed one.

Warnings, Precautions and Side Effects of Carfilzomib

Warnings

One of the most important warnings associated with carfilzomib is the risk of heart-related side effects, such as heart failure, heart attack, and arrhythmias. This medication increases the risk of infections, which can be severe or life-threatening. Other potential side effects are lung-related side effects, such as shortness of breath and pulmonary hypertension, as well as kidney and liver toxicity. It is also important to note that carfilzomib can cause fetal harm and should not be used during pregnancy.

Precautions

If you have any pre-existing heart conditions or risk factors for heart disease should be closely monitored during treatment with carfilzomib, and appropriate precautions should be taken to minimize the risk of cardiac events. You will be monitored closely for signs of infection, and appropriate prophylactic medications may be prescribed to help prevent infections. Patients with pre-existing lung, kidney, or liver conditions may be at increased risk of these side effects and should be closely monitored during treatment. Women of childbearing age should use effective contraception during treatment, and men should use condoms during sexual activity to prevent pregnancy.

Side Effects

The most common side effects of carfilzomib include fatigue, nausea, vomiting, diarrhea, low blood cell counts, fever, headache, difficulty breathing, cough, muscle weakness or pain, rash, and back pain. While these side effects are generally mild, some patients may experience more serious side effects, such as cardiac events like heart failure or heart attack, blood clotting disorders or bleeding, acute kidney injury, lung damage or inflammation, infections, or tumor lysis syndrome, which can occur when cancer cells break down rapidly.

Word Of Advice

It is important to take the Carfilzomib as directed by a healthcare professional. Patients should also inform their doctor of any pre-existing medical conditions and any other medications they may be taking. It is important to be aware of the potential side effects and to report any concerns to your healthcare provider. Pregnant or breastfeeding women should consult their doctor before taking it, as the drug may pose a risk to the baby. There are no specific dietary restrictions for patients taking this medication. However, it is generally recommended that patients with cancer maintain a healthy and balanced diet to support their overall health and well-being. Drinking plenty of water and other fluids, such as clear broths or herbal teas, can help to prevent dehydration.

Frequently Asked Question

Carfilzomib is often combined with other cancer treatments, such as chemotherapy or immunotherapy. Your healthcare provider will determine the most appropriate treatment plan based on the specifics of your cancer diagnosis and individual health status.
While carfilzomib is an effective treatment for multiple myeloma, it is not considered a cure. However, it can help to slow the progression of cancer and improve the quality of life for many patients.
It is important to consult with your healthcare provider before taking any over-the-counter medications while on carfilzomib, as some may interact with the treatment and affect its effectiveness.
Hair loss is not a common side effect of treatment with carfilzomib. However, other side effects, such as fatigue and nausea, may affect your quality of life during treatment.

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.