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Botulinum Toxin Type A

This page contains brief details about the drug botulinum toxin type a, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Botulinum Toxin Type A is a neuromuscular blocking agent which was approved for its medical use in 1989.

Mechanism of Action of Botulinum Toxin Type A

Botulinum Toxin Type A is an acetylcholine release inhibitor and neuromuscular blocking agent. It works by preventing the release of acetylcholine into the space between neurons, thereby stopping neuromuscular transmission. When injected into a muscle, it reduces the frequency of muscle contractions and nerve impulses, ultimately lowering muscle spasms and alleviating symptoms of neurological conditions.

AVAILABLE BRANDS

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Xeomin 50IU Injection
MODIMUNDI PHARMA PVT LTD ₹11,300.00
Xeomin 100IU Injection
MODIMUNDI PHARMA PVT LTD ₹20,511.00
Botox 100IU Injection
ALLERGAN INDIA PVT LTD ₹18,000.00
Intabot 100IU Injection
INTAS PHARMACEUTICALS LTD ₹11,420.00

Uses of Botulinum Toxin Type A

Botulinum Toxin Type A Injection is designed to treat urinary incontinence caused by an overactive bladder and neurological conditions such as spinal cord injury and multiple sclerosis. It is also indicated for treating eye spasms (blepharospasm), upper and lower limb spasms in pediatric patients and stroke survivors. Additionally, this injection is used to manage cervical dystonia, severe underarm sweating, and chronic migraines lasting over 4 hours a day for at least 15 days a month.

Botulinum Toxin Type A Drug administaration and Dosage available

A healthcare professional will administer Botulinum Toxin Type A as an intramuscular injection. The dosage and number of injections will vary based on the patient’s age and medical condition. This injection is available as a purified neurotoxin complex powder in doses of 50 IU, 100 IU, and 200 IU.

Warnings, Precautions and Side Effects of Botulinum Toxin Type A

Warnings

Contact your doctor immediately if you experience shortness of breath, fever, or any other discomfort while undergoing treatment with Botulinum Toxin Type A Injection. During treatment, your doctor may periodically monitor your blood cell counts, electrolytes, and kidney function to prevent serious complications. Inform your doctor if you have a history of neurological disorders, asthma, bleeding disorders, urinary tract infections, heart failure, or liver problems. Additionally, notify your healthcare provider if you are scheduled for surgery or a dental procedure while being treated with Botulinum Toxin Type A.

Precautions

There is no evidence regarding the impact of Botulinum Toxin Type A on pregnancy and breastfeeding. It is advisable to tell your healthcare provider before starting treatment with Botulinum Toxin Type A Injection if you are pregnant, breastfeeding, or planning to have a baby.

Side Effects

The common side effects that are likely to occur while you are on the treatment with Botulinum Toxin Type A Injection are urinary tract infection, urinary retention, dysuria, neck pain, headache, pain in extremities, upper respiratory tract infection, flu, back pain, rhinitis, injection site pain, dry mouth, fever, nausea, vision trouble, and muscle weakness. If you experience symptoms such as breathing difficulty, rashes, wheezing, trouble swallowing, report to your doctor immediately.

Word Of Advice

Botulinum Toxin Type A can make you feel dizzy, tired and make your vision blurry. Hence, you should avoid driving or handling machines while on this treatment. Apply cool compress at the injection site to reduce the pain.

Frequently Asked Question

Tell your healthcare provider before starting treatment with Botulinum Toxin Type A if you have any allergies, are pregnant, breastfeeding or taking prescription medicines or supplements.
The effect of Botulinum toxin type A Injection typically lasts for about 8 to 12 weeks.
Do not lie down for at least 3 hours after receiving Botulinum Toxin Type A Injection and avoid going to saunas and hot tubs for 4 hours after receiving the injection.
Do not receive Botulinum Toxin type A Injection if you are allergic to Botox, Botox cosmetic or any of its ingredients, have a skin infection at the planned site of injection or if you are undergoing treatment for urinary tract infection.
When the Botox Injection affects the areas away from the site of injection, it results in condition called botulism. It is characterized by symptoms such as changes in voice, trouble saying words, drooping eyelids, double vision, loss of bladder control, difficulty breathing and swallowing.

Disclaimer

The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.