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ATRACURIUM BESYLATE INJ

This page contains brief details about the drug atracurium besylate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

The U.S. FDA approved Atracurium Besylate on July 18, 1997. Atracurium Besylate belongs to the medication class known as muscle relaxants. It works by blocking the transmission of nerve signals to the muscles.

Mechanism of Action of Atracurium Besylate

Atracurium Besylate impedes the flow of nerve signals to the muscles. Typically, when a muscle receives a nerve signal, it triggers the release of a neurotransmitter known as acetylcholine. This neurotransmitter then connects with receptors on the muscle cells, prompting them to contract. Atracurium operates by attaching itself to these acetylcholine receptors in a competitive manner, thus blocking acetylcholine from binding and preventing the muscles from contracting.

AVAILABLE BRANDS

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Artacil 25mg 2.5ml Injection
NEON LABORATORIES LTD ₹51.00
Artacil 50mg 5ml Injection
NEON LABORATORIES LTD ₹99.00
Acris 25MG 2.5ML Injection
GLAND PHARMA LTD ₹79.00
Atacurium 10mg 5ml Injection
THEMIS MEDICARE LIMITED ₹100.00

Uses of Atracurium Besylate

Atracurium Besylate finds its application across a wide range of medical environments, such as in surgical operations, various medical procedures, and within intensive care units. Its specific use during general anesthesia is to ease the process of tracheal intubation (the placement of a tube into the windpipe) and to assist in controlled breathing.

Atracurium Besylate Drug administaration and Dosage available

A healthcare professional will administer Atracurium Besylate to you in a hospital environment, typically through an intravenous route (into a vein). The specific dosage, method of administration, and how often it is given will be determined by your doctor, taking into account your medical condition and various other factors.

Warnings, Precautions and Side Effects of Atracurium Besylate

Warnings

Do not take Atracurium Besylate if you have an allergy to it or any of its components. It’s important to avoid this medication if you’re allergic to any part of it. Before you begin treatment, make sure to inform your doctor about any neuromuscular conditions you have, like myasthenia gravis or Eaton-Lambert syndrome, which affect muscle function or the nervous system’s control over muscles. Also, let your doctor know if you suffer from a severe electrolyte imbalance, have widespread cancer (known as carcinomatosis), or are particularly sensitive to histamine. Atracurium Besylate is not advised for use in neonates (babies younger than one month). For newborns or premature infants, if its use is absolutely necessary, the dosage should be adjusted and significantly reduced.

Precautions

Inform your doctor if you are pregnant, considering pregnancy, suspect you might be pregnant, or if you are breastfeeding. It’s also important to disclose any past allergic reactions, asthma, or episodes of bronchospasm, as well as any history of burns or conditions associated with insufficient blood volume (hypovolemia). Should you have any additional queries or concerns, don’t hesitate to speak with your doctor.

Side Effects

The most common side effects of Atracurium Besylate are tachycardia (rapid heartbeat), temporary hypotension (low blood pressure), wheezing, bronchospasm (asthma-like symptoms), skin flushing, and urticaria (nettle rash).

Word Of Advice

Make sure to alert your doctor immediately if you encounter any severe side effects to mitigate potential health risks. Before initiating treatment, it’s crucial to disclose all existing medical conditions to your doctor. This step is vital for ensuring Atracurium’s safe and effective application during medical procedures. Should you suffer from any significant adverse effects, inform your doctor promptly. Your healthcare provider will then decide if adjustments to your dosage are necessary. For more details or guidance, do not hesitate to reach out to your doctor. Keep the medication away from pets and children, ensuring it’s neither visible nor accessible to them. Avoid freezing the medication and store it at temperatures between 2°C and 8°C. Always verify the medicine’s expiry date prior to use.

Frequently Asked Question

Atracurium Besylate is used in various medical settings, including surgeries, other medical procedures, and intensive care units. It is used specifically during general anesthesia to facilitate tracheal intubation (insertion of a tube into the windpipe) and to enable controlled ventilation.
No, Atracurium Besylate should only be administered by healthcare professionals in a clinical setting. Please do not self-administer.
Atracurium Besylate injection should not be given to pregnant or breastfeeding women unless recommended by a doctor.
Before starting the treatment, it is essential to consult your doctor, as they can interact with various other medications. Getting suggestions from your doctor will help to ensure the safe and appropriate use of Atracurium Besylate with your current medication regimen.