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Introduction to Nefrogard Tablet
Nefrogard Tablet is a nutritional supplement containing the active ingredient Alpha Ketoanalogue, classified as an amino acid medication. Prescribed in conjunction with a protein-restricted diet, it aims to slow the progression of chronic kidney disease (CKD). By decreasing uraemic symptoms and enhancing nutritional status, it helps mitigate metabolic complications in CKD patients. The mechanism involves reducing urea levels in the bloodstream, consequently slowing the advancement of kidney disease and postponing the necessity for long-term dialysis.
Refrain from taking Nefrogard Tablet if you are allergic to Alpha Ketoanalogue or any of its components. Avoid this medication if you have hypercalcemia (elevated calcium levels) or experience abnormal heartbeats, as its administration may lead to increased calcium levels in the blood and irregular heartbeats. Throughout the treatment, your doctor may advise regular monitoring of serum calcium levels. Inform your doctor if you are pregnant or breastfeeding before initiating this medication.
Uses of Nefrogard Tablet
- Treatment of Chronic kidney disease
- Delaying disease progression and the onset of dialysis
- Reducing metabolic complications due to renal insufficiency
- Reduction of uraemic symptoms
Therapeutic Effects of Nefrogard Tablet
Nefrogard Tablet is categorized as a nutritional supplement that functions through similar catabolic pathways as amino acids. This heightened protein metabolism supports enhanced renal function, consequently slowing down the advancement of chronic kidney disease. Moreover, it ensures the intake of essential amino acids.
Interaction of Nefrogard Tablet with other drugs
Notify your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you are currently taking or have taken before starting the treatment. Some medications may interact with Nefrogard Tablet, potentially leading to undesirable side effects.
More Information about Nefrogard Tablet
- Keep out of sight and reach of pets and children.
- Do not freeze the medicine.
- Do not store above 30°C.
- Always check the expiry date before consuming it.
How to consume Nefrogard Tablet
Take Nefrogard Tablet as directed by your physician. Typically, the tablets can be taken with or without food. Do not crush, chew, or open the medicine. The appropriate dosage and duration will be determined by your physician based on factors such as age, body weight, and the specific disease condition. Only discontinue the tablet if your doctor instructs you to do so.
Safety Advices for Nefrogard Tablet
Pregnancy
There is limited information on the use of Nefrogard Tablet during pregnancy. Inform your healthcare professional if you are pregnant, planning to conceive, or suspect that you may be pregnant.
Breast Feeding
There is limited information on the use of Nefrogard Tablet during breastfeeding. Therefore, before initiating the treatment, inform your doctor if you are breastfeeding. For additional information, consult your doctor.
Lungs
The safety of Nefrogard Tablet in patients with lung problems is unknown. Notify your physician if you have any lung disease before commencing the treatment, and contact your doctor if you experience any symptoms related to your lungs.
Liver
The safety of Nefrogard Tablet in patients with liver problems is unknown. Inform your physician if you have any liver disease before initiating the treatment, and contact your doctor if you experience any symptoms related to your liver.
Alcohol
The safety of consuming alcohol while taking Nefrogard Tablet is unknown. Please consult with your physician for guidance.
Driving
The safety of consuming alcohol with Nefrogard Tablet is not known. For more information, consult your doctor.
Side Effects of Nefrogard Tablet
Side effects are unintended symptoms triggered by medications. While all medications can cause side effects, not everyone experiences them.
Common:
- Increased calcium level in the blood
Word of Advice
Notify your doctor about any other kidney disease and all underlying medical conditions. Refrain from discontinuing Nefrogard Tablet unless advised by your doctor. Avoid doubling the dose to compensate for a missed one. Report any serious side effects to your doctor, who will guide you on necessary dose adjustments. For additional information, contact your doctor.
FAQs
Q 1. How to manage the side effects of the Nefrogard Tablet?
To address potential side effects of the Nefrogard Tablet, adhere to the prescribed dosage, promptly report any side effects, stay hydrated, and regularly monitor your calcium levels. Sustain a healthy lifestyle and attend scheduled follow-up appointments.
Q 2. What is a Nefrogard Tablet?
Nefrogard Tablet are nutritional supplements comprising essential amino acids and keto analogs. They enhance protein metabolism and aid renal function in individuals with chronic kidney disease. Prescribed to manage and slow the progression of kidney disease, they play a crucial role in supporting overall kidney health.
Q 3. Can you take Nefrogard Tablet when pregnant?
Seek advice from your healthcare professional regarding the use of Nefrogard Tablet during pregnancy. The potential benefits and risks should be thoroughly evaluated, and your doctor will recommend taking this medicine only if deemed necessary.
Q 4. What are the side effects of Nefrogard Tablet?
Elevated calcium levels in the blood are a common side effect of Nefrogard Tablet. It is essential to consult your doctor for any concerns or persistent side effects.
Q 5. What should I do if I miss a dose of Nefrogard Tablet?
If you miss a dose of the capsule, take it as soon as possible. However, if it’s close to the time for your next dose, skip the missed dose and resume your regular schedule. Avoid doubling the dose of the Nefrogard Tablet.
Fact Box of Nefrogard Tablet
Molecule name: Alpha Ketoanalogue
Pharmacological class: Amino Acids
Therapeutic class: Nutritional supplement
Indications:
1. Treatment of Chronic kidney disease
2. Delaying disease progression and the onset of dialysis
3. Reducing metabolic complications due to renal insufficiency
4. Reduction of uraemic symptoms
1. Treatment of Chronic kidney disease
2. Delaying disease progression and the onset of dialysis
3. Reducing metabolic complications due to renal insufficiency
4. Reduction of uraemic symptoms
References
- Rivpra formulation PVT LTD, [ Revised on Jan 2021] [Accessed on 15th June 2023], https://www.centaurpharma.com/downloads/2021/nephrology/NEFROGARD.pdf
- Alexander Zemchenkov, Irina N.Konakova; Efficacy of the Essential Amino Acids and Keto-Analogues on the CKD progression rate in real practice in Russia – city nephrology registry data for outpatient clinic; BMC Nephrology; [Published on 07/07/2016]; [Accessed on 15th June 2023] https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-016-0281-z
- Arun Sharma et al; Rationale of α-Ketoanalogue Supplemented with Low Protein Diet for the Treatment of Chronic Kidney Disease; Journal of Karnali Academy of Health Sciences; [Published on 09/01/2021]; [Accessed on 15th June 2023]; https://jkahs.org.np/jkahs/index.php/jkahs/article/view/415/222
- Che-Hsiung Wu et al; Ketoanalogues supplementation decreases dialysis and mortality risk in patients with anemic advanced chronic kidney disease; [Published on 05/05/2021]; [Accessed on 15th June 2023]; http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5419544/
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